Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19423 | 0.97 | — | — | |
| SCHEMBL597935 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL9316175 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL1966887 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| Water SCHEMBL7871948 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL8101936 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL1245971 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL2927603 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL1171104 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL999954 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230144-B2 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX INC. (US) | 2007-06-12 | — | — | US | disclosed |
| US-7166743-B2 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7001969-B2 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX INC. (US) | 2006-02-21 | — | — | US | disclosed |
| US-6933404-B2 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX INC. (US) | 2005-08-23 | — | — | US | disclosed |
| US-20050182235-A1 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX INC., A DELAWARE CORPORATION | 2005-08-18 | — | — | US | disclosed |
| US-6897338-B2 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX, INC. (US) | 2005-05-24 | — | — | US | disclosed |
| US-20050101760-A1 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX INC. (US) | 2005-05-12 | — | — | US | disclosed |
| US-6844447-B2 | Methods of making intermediates from polyhydroxyalkanoates | METABOLIX INC. (US) | 2005-01-18 | — | — | US | disclosed |
| US-20030162851-A1 | Methods of making intermediates from polyhydroxyalkanoates | CJ CHEILJEDANG CORPORATION (KR) | 2003-08-28 | — | — | US | disclosed |
| US-20030158274-A1 | Methods of making intermediates from polyhydroxyalkanoates | CJ CHEILJEDANG CORPORATION (KR) | 2003-08-21 | — | — | US | disclosed |
| US-20030158441-A1 | Methods of making intermediates from polyhydroxyalkanoates | CJ CHEILJEDANG CORPORATION (KR) | 2003-08-21 | — | — | US | disclosed |
| US-20030144551-A1 | Methods of making intermediates from polyhydroxyalkanoates | CJ CHEILJEDANG CORPORATION (KR) | 2003-07-31 | — | — | US | disclosed |
| WO-2003051813-A1 | METHODS OF MAKING INTERMEDIATES FROM POLYHYDROXYALKANOATES | METABOLIX, INC. (US) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158441-A1 | Methods of making intermediates from polyhydroxyalkanoates | HMBS, COASY, PGLS | EGLN1 1200/4885KDM4E 3471/4885KDM6B 1591/4885 |
| US-20030144551-A1 | Methods of making intermediates from polyhydroxyalkanoates | HMBS, COASY, PGLS | EGLN1 1200/4885KDM4E 3471/4885KDM6B 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.