Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431970 | 0.91 | KDM4C (0.50) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL27031980 | 0.91 | KDM4C (0.47) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL6879618 | 0.90 | KDM4C (0.58) | KDM4CL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL21068940 | 0.89 | MEN1 (0.47) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL21068739 | 0.89 | MEN1 (0.50) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL5423863 | 0.89 | KDM4C (0.50) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL24574174 | 0.88 | MEN1 (0.49) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL21458948 | 0.88 | MEN1 (0.46) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL22787023 | 0.88 | MEN1 (0.52) | KDM4CL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL21068789 | 0.88 | MEN1 (0.49) | KDM4CL3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135490-A1 | Phenetanolamine derivatives | GLAXO GROUP LIMITED (GB) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135490-A1 | Phenetanolamine derivatives | ADRB2, ADRB1, ADRB3 | KDM4C 3939/4885L3MBTL1 4280/4885TDP1 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.