Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037987 | 0.89 | ESR1 (0.70) | TSHRTP53ESR1ESR2LMNA | |
| SCHEMBL2297964 | 0.89 | ESR1 (0.60) | TSHRTP53ESR1ESR2LMNA | |
| SCHEMBL10499313 | 0.85 | NPC1 (0.61) | TSHRTP53NPC1RAB9APOLB | |
| SCHEMBL28388652 | 0.85 | MAPT (0.65) | ESR1ESR2NPC1RAB9APOLB | |
| SCHEMBL9481140 | 0.81 | ESR1 (0.59) | TSHRTP53ESR1ESR2LMNA | |
| SCHEMBL9739234 | 0.81 | TSHR (0.63) | TSHRTP53ESR1ESR2LMNA | |
| SCHEMBL11847134 | 0.81 | TSHR (0.63) | TSHRTP53ESR1ESR2LMNA | |
| SCHEMBL1096587 | 0.81 | CYP2D6 (0.44) | TSHRESR1ESR2LMNAPOLB | |
| SCHEMBL984298 | 0.81 | CYP2D6 (0.44) | TSHRESR1ESR2LMNAKMT2A | |
| SCHEMBL27840777 | 0.81 | CYP2D6 (0.44) | TSHRESR1ESR2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705289-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | Terran Biosciences Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226691-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-101786934-B | Preparation method of aromatic formaldehyde | UNIV JIANGXI NORMAL SCI & TECH | 2012-10-10 | — | — | CN | disclosed |
| CN-101786934-A | Preparation method of aromatic formaldehyde | JIANGXI NORMAL UNIVERSITY OF S | 2010-07-28 | — | — | CN | disclosed |
| US-20070082922-A1 | Huperzine a prodrugs and uses thereof | PAN BAI-CHUAN | 2007-04-12 | — | — | US | disclosed |
| US-20070082922-A1 | Huperzine a prodrugs and uses thereof | PAN BAI-CHUAN | 2007-04-12 | — | — | US | disclosed |
| US-20070082922-A1 | Huperzine a prodrugs and uses thereof | PAN BAI-CHUAN | 2007-04-12 | — | — | US | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082922-A1 | Huperzine a prodrugs and uses thereof | APP, ACHE, PSEN1 | TSHR 4464/4885TP53 2620/4885ESR1 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.