Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418762 | 0.84 | ALDH1A1 (0.39) | SIGMAR1 | |
| SCHEMBL5412060 | 0.84 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL2923881 | 0.84 | TSHR (0.34) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6757419 | 0.82 | TSHR (0.33) | SIGMAR1 | |
| SCHEMBL6068780 | 0.80 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL5422833 | 0.78 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL14445317 | 0.78 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL5439394 | 0.77 | CYP3A4 (0.38) | SIGMAR1 | |
| SCHEMBL3944376 | 0.76 | TSHR (0.32) | SIGMAR1 | |
| SCHEMBL6068593 | 0.74 | SIGMAR1 (0.40) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |