Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 7/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.64 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 7/20 | 0.38 |
| ▸ | RXRB | P28702 | 6/20 | 0.38 |
| ▸ | RXRG | P48443 | 5/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423557 | 1.00 | CYP26A1 (0.64) | CYP26A1CYP3A4CYP26B1CA12CA1 | |
| SCHEMBL8908692 | 0.89 | CYP26A1 (0.77) | CYP26A1CYP3A4CYP26B1CA12CA1 | |
| SCHEMBL8908697 | 0.89 | CYP26A1 (0.77) | CYP26A1CYP3A4CYP26B1CA12CA1 | |
| SCHEMBL5421801 | 0.89 | CYP26A1 (0.62) | CYP26A1CYP3A4CYP26B1PPARGRXRA | |
| SCHEMBL5421804 | 0.89 | CYP26A1 (0.62) | CYP26A1CYP3A4CYP26B1PPARGRXRA | |
| SCHEMBL5431263 | 0.88 | CYP3A4 (0.61) | CYP26A1CYP3A4CYP26B1CA12CA1 | |
| SCHEMBL5429594 | 0.87 | CYP26A1 (0.65) | CYP26A1CYP3A4CYP26B1CA12CA1 | |
| SCHEMBL5429598 | 0.87 | CYP26A1 (0.65) | CYP26A1CYP3A4CYP26B1CA12CA1 | |
| SCHEMBL5081220 | 0.87 | CYP26A1 (0.76) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL5081216 | 0.87 | CYP26A1 (0.76) | CYP26A1CYP3A4CYP26B1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249710-A1 | Biaromatic compounds and cosmetic/pharmaceutical applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-10-25 | — | — | US | claimed |
| US-20070249710-A1 | Biaromatic compounds and cosmetic/pharmaceutical applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249710-A1 | Biaromatic compounds and cosmetic/pharmaceutical applications thereof | RARG, RARA, RARB | CYP26A1 378/4885CYP3A4 2007/4885CYP26B1 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.