Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33797 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KDM4ETDP1LMNAALOX15 | |
| SCHEMBL3941204 | 0.89 | MGMT (0.33) | ALDH1A1MGMT | |
| Hydrochloric Acid SCHEMBL5414502 | 0.88 | ALDH1A1 (0.36) | ALDH1A1KDM4ETDP1LMNAALOX15 | |
| Hydrochloric Acid SCHEMBL6282164 | 0.88 | ALDH1A1 (0.36) | ALDH1A1KDM4ETDP1LMNAALOX15 | |
| SCHEMBL5418741 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4ETDP1LMNAALOX15 | |
| SCHEMBL14445349 | 0.83 | ALDH1A1 (0.34) | ALDH1A1KDM4ETDP1LMNAALOX15 | |
| SCHEMBL5423811 | 0.83 | ALDH1A1 (0.34) | ALDH1A1KDM4ETDP1LMNAALOX15 | |
| SCHEMBL5421688 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL5418484 | 0.83 | HCAR3 (0.34) | SMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL5416465 | 0.83 | MERTK (0.34) | MGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |