Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333120 | 0.81 | FGFR1 (0.50) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5435825 | 0.81 | FGFR1 (0.47) | SIRT6ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14224669 | 0.80 | MEN1 (0.49) | MAPTALDH1A1NPBWR1MEN1KMT2A | |
| SCHEMBL4258177 | 0.80 | NPBWR1 (0.58) | MAPTALDH1A1LMNANPBWR1MEN1 | |
| SCHEMBL1552598 | 0.78 | MAPT (0.54) | SIRT6MAPTALDH1A1LMNANPBWR1 | |
| SCHEMBL5333969 | 0.78 | CHEK2 (0.47) | MAPTALDH1A1NPBWR1MEN1KMT2A | |
| SCHEMBL27521866 | 0.77 | NPBWR1 (0.53) | SIRT6MAPTALDH1A1LMNANPBWR1 | |
| SCHEMBL14669420 | 0.77 | MAPT (0.53) | SIRT6MAPTALDH1A1LMNANPBWR1 | |
| SCHEMBL3381581 | 0.75 | FGFR1 (0.71) | PDGFRBFGFR1KDR | |
| SCHEMBL5559865 | 0.75 | MEN1 (0.47) | MAPTALDH1A1LMNANPBWR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |