Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601049 | 0.91 | CHEK2 (0.58) | CHEK2KMT2AMEN1MAPTPOLB | |
| SCHEMBL5559865 | 0.88 | MEN1 (0.47) | CHEK2KMT2AMEN1MAPTPOLB | |
| SCHEMBL14224669 | 0.85 | MEN1 (0.49) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL8601035 | 0.83 | KMT2A (0.43) | CHEK2KMT2AMEN1MAPTPOLB | |
| SCHEMBL7471355 | 0.83 | MAPT (0.43) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7473157 | 0.81 | MAPT (0.43) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7465939 | 0.80 | MAPT (0.43) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7470258 | 0.80 | HPGD (0.46) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7470356 | 0.80 | TDP1 (0.48) | CHEK2KMT2AMEN1MAPTPOLB | |
| SCHEMBL15233046 | 0.80 | IRAK4 (0.54) | CHEK2KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0776891-B1 | Pyrrolylbenzimidazole derivatives | MITSUI CHEMICALS INC (JP) | 1999-02-10 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5808087-A | ANTITUMOR, ANTICANCER AGENTS | MITSUI CHEMICALS, INC. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0776891-A1 | Pyrrolylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-06-04 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |