SCHEMBL542475

SCHEMBL542475

CCCOC[Si](CC1CO1)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL637425 0.78 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL17686818 0.77 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1TDP1
SCHEMBL3068427 0.77 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL27653146 0.72 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1TDP1
SCHEMBL5266721 0.71 TSHR (0.47) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL5270708 0.70 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL671583 0.69 ALDH1A1 (0.30) ALDH1A1
SCHEMBL143771 0.68
SCHEMBL1224808 0.67 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL7688095 0.67 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250019578-A1 ACRYLIC COPOLYMER COMPOSITIONS FOR USE AS SEALANTS ROHM AND HAAS COMPANY 2025-01-16 US disclosed
EP-4444770-A1 ACRYLIC COPOLYMER COMPOSITIONS FOR USE AS SEALANTS Rohm and Haas Company (US) 2024-10-16 EP disclosed
WO-2023107204-A1 ACRYLIC COPOLYMER COMPOSITIONS FOR USE AS SEALANTS ROHM AND HAAS COMPANY (US) 2023-06-15 WO disclosed
US-9777166-B2 Plasticizer free caulks and sealants comprising waterborne acrylic polymeric composites and methods for making the same Rohnm and Haas Company (US) 2017-10-03 US disclosed
EP-2935374-B1 PLASTICIZER FREE CAULKS AND SEALANTS COMPRISING WATERBORNE ACRYLIC POLYMERIC COMPOSITES AND METHODS FOR MAKING THE SAME ROHM & HAAS (US) 2017-02-01 EP disclosed
US-20160194505-A1 PLASTICIZER FREE CAULKS AND SEALANTS COMPRISING WATERBORNE ACRYLIC POLYMERIC COMPOSITES AND METHODS FOR MAKING THE SAME ROHM AND HAAS COMPANY 2016-07-07 US disclosed
EP-2935374-A1 PLASTICIZER FREE CAULKS AND SEALANTS COMPRISING WATERBORNE ACRYLIC POLYMERIC COMPOSITES AND METHODS FOR MAKING THE SAME Rohm and Haas Company (US) 2015-10-28 EP disclosed
EP-2686283-B1 HIGH SOLIDS PIGMENTED LATEX COMPOSITIONS WACKER CHEMICAL CORP (US) 2015-03-04 EP disclosed
WO-2014099575-A1 PLASTICIZER FREE CAULKS AND SEALANTS COMPRISING WATERBORNE ACRYLIC POLYMERIC COMPOSITES AND METHODS FOR MAKING THE SAME ROHM AND HAAS COMPANY (US) 2014-06-26 WO disclosed
EP-2686283-A1 HIGH SOLIDS PIGMENTED LATEX COMPOSITIONS Wacker Chemical Corporation (US) 2014-01-22 EP disclosed
CN-103476730-A High solids pigmented latex compositions WACKER CHEMICAL CORP 2013-12-25 CN disclosed
WO-2012128993-A1 HIGH SOLIDS PIGMENTED LATEX COMPOSITIONS WACKER CHEMICAL CORPORATION (US) 2012-09-27 WO disclosed
US-8193278-B2 Plasticizer free caulks and sealants having improved aged wet adhesion ROHM AND HAAS COMPANY (US) 2012-06-05 US disclosed
EP-2281856-B1 Plasticizer free caulk and sealants having improved aged wet adhesion ROHM & HAAS (US) 2012-02-08 EP disclosed
US-20110034621-A1 PLASTICIZER FREE CAULKS AND SEALANTS HAVING IMPROVED AGED WET ADHESION ROHM AND HASS COMPANY (US) 2011-02-10 US disclosed
EP-2281856-A1 Plasticizer free caulk and sealants having improved aged wet adhesion Rohm and Haas Company (US) 2011-02-09 EP disclosed