SCHEMBL637425

SCHEMBL637425

CO[Si](CC1CO1)(CC1CO1)OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3068427 0.88 SMN1; SMN2 (0.33) ALDH1A1TSHRTDP1MAPK1SMN1; SMN2
SCHEMBL671583 0.84 ALDH1A1 (0.30) ALDH1A1
SCHEMBL17686818 0.84 SMN1; SMN2 (0.35) ALDH1A1TDP1SMN1; SMN2
SCHEMBL27731585 0.79 ALDH1A1 (0.36) ALDH1A1TSHRTDP1MAPK1SMN1; SMN2
SCHEMBL3068447 0.79
SCHEMBL203335 0.79 ALDH1A1 (0.36) ALDH1A1TSHRTDP1MAPK1SMN1; SMN2
SCHEMBL198113 0.79 ALDH1A1 (0.36) ALDH1A1TSHRTDP1MAPK1SMN1; SMN2
SCHEMBL542475 0.78 SMN1; SMN2 (0.39) ALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL1225396 0.75 ALDH1A1 (0.36) ALDH1A1TSHRTDP1MAPK1SMN1; SMN2
Cyclopropane SCHEMBL3461994 0.75 ALDH1A1 (0.33) ALDH1A1TSHRTDP1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329263-B2 Method of coating a particle AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-12-11 US disclosed
EP-2015876-B1 COATING COMPOSITIONS SUITABLE FOR USE AS A WOOD STAIN AND/OR TONER PPG IND OHIO INC (US) 2012-02-22 EP disclosed
US-20100276310-A1 METHOD OF COATING A PARTICLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-04 US disclosed
US-7691484-B2 Coating compositions suitable for use as a wood stain and/or toner PPG INDUSTRIES OHIO, INC. (US) 2010-04-06 US disclosed
US-7579073-B2 Coating compositions suitable for use as a wood stain and/or toner PPG INDUSTRIES OHIO, INC. (US) 2009-08-25 US disclosed
WO-2009029053-A1 METHOD OF COATING A PARTICLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-03-05 WO disclosed
EP-2015876-A1 COATING COMPOSITIONS SUITABLE FOR USE AS A WOOD STAIN AND/OR TONER PPG Industries Ohio, Inc. (US) 2009-01-21 EP disclosed
EP-1899426-B1 COATING COMPOSITIONS SUITABLE FOR USE AS A WOOD STAIN AND/OR TONER PPG IND OHIO INC (US) 2008-11-05 EP disclosed
US-7351475-B2 Film-forming resin, radiation cure initiator, colorant, and diluent; free of radiation curable material; multilayer composite coating with sealer and/or topcoat deposited from a radiation curable composition PPG INDUSTRIES OHIO, INC. (US) 2008-04-01 US disclosed
EP-1899426-A2 COATING COMPOSITIONS SUITABLE FOR USE AS A WOOD STAIN AND/OR TONER PPG Industries Ohio, Inc. (US) 2008-03-19 EP disclosed
US-5141802-A Heat resistant PPG INDUSTRIES, INC. (US) 1992-08-25 US disclosed
EP-0353493-A1 Chemically treated shapes, fillers and reinforcement for polymer matrices PPG INDUSTRIES, INC. (US) 1990-02-07 EP disclosed
EP-0220513-A2 Stampable laminates of glass fiber reinforced poly(ethylene terephthalate) PPG INDUSTRIES, INC. (US) 1987-05-06 EP disclosed
EP-0084152-B1 SIZED GLASS FIBERS FOR THERMOPLASTIC REINFORCEMENT PPG INDUSTRIES, INC. (US) 1986-04-30 EP disclosed
EP-0083057-B1 AQUEOUS SIZED GLASS FIBERS FOR REINFORCING THERMOSETTING POLYMERS PPG INDUSTRIES, INC. (US) 1985-11-21 EP disclosed
EP-0084152-A1 Sized glass fibers for thermoplastic reinforcement PPG INDUSTRIES, INC. (US) 1983-07-27 EP disclosed
US-4394475-A WAX, POLYETHYLENE PPG INDUSTRIES, INC. (US) 1983-07-19 US disclosed
US-4394418-A Aqueous sizing composition and glass fibers made therewith for reinforcing thermosetting polymers PPG INDUSTRIES, INC. (US) 1983-07-19 US disclosed
EP-0083057-A1 Aqueous sized glass fibers for reinforcing thermosetting polymers PPG INDUSTRIES, INC. (US) 1983-07-06 EP disclosed
US-4374177-A CONTAINING A POLYURETHANE, POLYEPOXIDE, POLYETHYLENE-CONTAINING POLYMER, WAX, AND COUPLING AGENT PPG INDUSTRIES, INC. (US) 1983-02-15 US disclosed