SCHEMBL5425655

SCHEMBL5425655

CC1=NN(c2ccccc2)CC1=O.[NaH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
ALDH1A1 P00352 6/20 0.43
KMT2A Q03164 6/20 0.43
MEN1 O00255 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
GAA P10253 3/20 0.43
KDM4E B2RXH2 3/20 0.43
CYP1A2 P05177 1/20 0.43
CHRM2 P08172 1/20 0.43
CYP3A4 P08684 1/20 0.43
CHRM1 P11229 1/20 0.43
TSHR P16473 1/20 0.43
PTGS1 P23219 1/20 0.43
DRD3 P35462 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAOB P27338 1/20 0.39
LOX P28300 2/20 0.39
LOXL3 P58215 1/20 0.39
LOXL4 Q96JB6 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820724 0.98 MAPT (0.44) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL7786530 0.83 F2 (0.42) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL11579395 0.80 KMT2A (0.51) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL8629565 0.80 POLB (0.50) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL8761202 0.78 MAPT (0.45) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL9805803 0.78 KMT2A (0.51) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL11290209 0.76 KMT2A (0.43) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL10481667 0.76 ELANE (0.45) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL3365280 0.76 NPC1 (0.41) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL3946803 0.76 MAOB (0.40) MAPTALDH1A1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070029059-A1 Enzymatic opacifying composition for paper, pulp or paperboard, processes using same and pulp, paper or paperboard produced therefrom TRI-TEX CO. INC. (CA) 2007-02-08 US disclosed