Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144089 | 0.78 | KMT2A (0.47) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL162737 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL4144275 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL18800846 | 0.68 | ALDH1A1 (0.36) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL17215600 | 0.68 | ALDH1A1 (0.36) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL20852785 | 0.66 | KMT2A (0.49) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL8565732 | 0.66 | CA12 (0.36) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL4156818 | 0.66 | PDK1 (0.51) | KDM4EGAAMAPK1CYP1A2CYP2C19 | |
| SCHEMBL10627226 | 0.66 | PTK2 (0.50) | KDM4EHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21543943 | 0.65 | ALDH1A1 (0.40) | ALDH1A1KDM4EGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | claimed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | claimed |