Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424703 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5425640 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5420036 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5428666 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5420039 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5417228 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5424608 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5434981 | 0.96 | ALDH1A1 (0.36) | SIGMAR1HRH4HRH3CHRM2ALDH1A1 | |
| SCHEMBL5427187 | 0.91 | ALDH1A1 (0.35) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL5425522 | 0.88 | HRH4 (0.45) | HRH4HRH3CHRM2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083965-B2 | Refrigerating machine oil | NIPPON OIL CORPORATION (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20070275865-A1 | Refrigerating Machine Oil | NIPPON OIL CORPORATION (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070257229-A1 | Refrigerating Machine Oil Composition | NIPPON OIL CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |