Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428696 | 0.99 | SIGMAR1 (0.43) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL5418045 | 0.99 | SIGMAR1 (0.43) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL5429115 | 0.99 | SIGMAR1 (0.43) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL5421147 | 0.99 | SIGMAR1 (0.43) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL5425512 | 0.99 | SIGMAR1 (0.43) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL5429044 | 0.99 | SIGMAR1 (0.43) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL5425750 | 0.99 | SIGMAR1 (0.43) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL5430548 | 0.96 | MPO (0.40) | SIGMAR1HTR2ASLC6A2MPOHTR1A | |
| SCHEMBL14953621 | 0.93 | SIGMAR1 (0.40) | SIGMAR1HRH4HRH3 | |
| SCHEMBL5433716 | 0.90 | HTR2A (0.45) | SIGMAR1HTR2ASLC6A2MPOHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083965-B2 | Refrigerating machine oil | NIPPON OIL CORPORATION (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20070275865-A1 | Refrigerating Machine Oil | NIPPON OIL CORPORATION (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070257229-A1 | Refrigerating Machine Oil Composition | NIPPON OIL CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |