Sugi Predict

Sugi Predict / Compounds / SCHEMBL542783

SCHEMBL542783

SCHEMBL542783

O=C(O)c1ccc(CO)cc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKAB2 O43741 1/20 0.49
▸ PRKAG1 P54619 1/20 0.49
▸ PRKAA2 P54646 1/20 0.49
▸ PRKAA1 Q13131 1/20 0.49
▸ PRKAG3 Q9UGI9 1/20 0.49
▸ PRKAG2 Q9UGJ0 1/20 0.49
▸ PRKAB1 Q9Y478 1/20 0.49
▸ EPHX2 P34913 1/20 0.48
▸ NR1H4 Q96RI1 1/20 0.48
▸ RARB P10826 2/20 0.47
▸ RARA P10276 1/20 0.47
▸ RARG P13631 1/20 0.47
▸ CA12 O43570 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ CA3 P07451 1/20 0.47
▸ CA4 P22748 1/20 0.47
▸ CA6 P23280 1/20 0.47
▸ CA7 P43166 1/20 0.47
▸ CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401542 0.86 MRGPRX4 (0.51) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL4048125 0.84 MAOB (0.54) EPHX2NR1H4RARBRARARARG
SCHEMBL31413134 0.84 DGAT1 (0.56) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL3932196 0.84 RARB (0.49) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL2855089 0.83 CA12 (0.50) CA12CA1CA2CA3CA4
SCHEMBL31490890 0.82 SRD5A2 (0.57) EPHX2NR1H4RARBRARARARG
SCHEMBL2845325 0.82 EPHX2 (0.47) EPHX2NR1H4RARBRARARARG
SCHEMBL13746058 0.82 EPHX2 (0.47) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL17049075 0.82 EPHX2 (0.47) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL506187 0.82 EPHX2 (0.47) EPHX2NR1H4RARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250354195-A1 METHOD OF SCREENING UNIV DUNDEE (GB) 2025-11-20 — — US disclosed
EP-3381913-B1 2-(((PYRROLIDIN-3-YL)CARBONYL)AMINO)-1H-IMIDAZOLE DERIVATIVES AS MELANOCORTIN RECEPTOR 1 (MCR1) AGONISTS FOR TREATING RHEUMATOID ARTHRITIS MITSUBISHI TANABE PHARMA CORP (JP) 2021-03-31 — — EP disclosed
US-10851119-B2 Boron-containing diacylhydrazines INTREXON CORPORATION (US) 2020-12-01 — — US disclosed
US-20200157122-A1 BORON-CONTAINING DIACYLHYDRAZINES INTREXON CORP (US) 2020-05-21 — — US disclosed
US-10464951-B2 Boron-containing diacylhydrazines INTREXON CORPORATION (US) 2019-11-05 — — US disclosed
US-10351759-B2 Methods of assessing oil field saturation through use of reactive partitioning tracers RESTRACK AS (NO) 2019-07-16 — — US disclosed
EP-3149103-B1 TRACERS RESTRACK AS (NO) 2018-05-30 — — EP disclosed
EP-2970106-B1 BORON-CONTAINING DIACYLHYDRAZINES INTREXON CORP (US) 2018-05-16 — — EP disclosed
US-20180079759-A1 Boron-Containing Diacylhydrazines INTREXON CORPORATION (US) 2018-03-22 — — US disclosed
US-20170198200-A1 TRACERS Resman Technology AS (NO) 2017-07-13 — — US disclosed
EP-2970106-A1 BORON-CONTAINING DIACYLHYDRAZINES Intrexon Corporation (US) 2016-01-20 — — EP disclosed
WO-2015181398-A1 TRACERS INSTITUTT FOR ENERGITEKNIKK (NO) 2015-12-03 — — WO disclosed
US-20150322092-A1 Boron-Containing Diacylhydrazines INTREXON CORPORATION (US) 2015-11-12 — — US disclosed
US-9127024-B2 Boron-containing diacylhydrazines INTREXON CORPORATION (US) 2015-09-08 — — US disclosed
WO-2015025164-A1 AMIDE DERIVATIVES AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-02-26 — — WO disclosed
WO-2014144380-A1 BORON-CONTAINING DIACYLHYDRAZINES INTREXON CORPORATION (US) 2014-09-18 — — WO disclosed
US-20140274954-A1 Boron-Containing Diacylhydrazines INTREXON CORPORATION 2014-09-18 — — US disclosed
EP-2415742-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR Sumitomo Chemical Company, Limited (JP) 2012-02-08 — — EP disclosed
WO-2001020995-A9 COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF UNIV WASHINGTON (US) 2002-11-14 — — WO disclosed
WO-2001020995-A1 COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF WASHINGTON UNIVERSITY (US) 2001-03-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10464951-B2 Boron-containing diacylhydrazines CD22, BRDT, BCR PRKAB2 4834/4885PRKAG1 4868/4885PRKAA2 4842/4885
US-20150322092-A1 Boron-Containing Diacylhydrazines CD22, BRDT, BCR PRKAB2 4834/4885PRKAG1 4868/4885PRKAA2 4842/4885
US-10851119-B2 Boron-containing diacylhydrazines CD22, BRDT, BCR PRKAB2 4834/4885PRKAG1 4868/4885PRKAA2 4842/4885
US-20200157122-A1 BORON-CONTAINING DIACYLHYDRAZINES CD22, BRDT, BCR PRKAB2 4834/4885PRKAG1 4868/4885PRKAA2 4842/4885
US-20140274954-A1 Boron-Containing Diacylhydrazines CD22, BRDT, BCR PRKAB2 4834/4885PRKAG1 4868/4885PRKAA2 4842/4885
US-20250354195-A1 METHOD OF SCREENING PAICS, COASY, ABCG2 PRKAB2 4065/4885PRKAG1 4028/4885PRKAA2 3485/4885
US-20180079759-A1 Boron-Containing Diacylhydrazines CD22, BRDT, BCR PRKAB2 4834/4885PRKAG1 4868/4885PRKAA2 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.