Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505565 | 0.87 | MRGPRX4 (0.49) | RARBRARARARGACMSDLCK | |
| SCHEMBL18740080 | 0.85 | RARB (0.49) | RARBRARARARGEPHX2NR1H4 | |
| SCHEMBL15583710 | 0.85 | RARB (0.65) | RARBRARARARGEPHX2NR1H4 | |
| SCHEMBL109609 | 0.84 | LCK (0.52) | ACMSDLCKKDM4EALDH1A1ALOX5 | |
| SCHEMBL542783 | 0.84 | PRKAB2 (0.49) | RARBRARARARGACMSDEPHX2 | |
| SCHEMBL27801899 | 0.83 | RARB (0.48) | RARBRARARARGEPHX2NR1H4 | |
| SCHEMBL6550099 | 0.83 | RARB (0.59) | RARBRARARARGEPHX2NR1H4 | |
| Hydrochloric Acid SCHEMBL12499520 | 0.83 | TDP1 (0.48) | RARBRARARARGEPHX2NR1H4 | |
| SCHEMBL3921415 | 0.81 | CYP4A11 (0.54) | KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7738951 | 0.80 | RARB (0.60) | RARBRARARARGEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565674-B | Octahydrocyclopenta [ c ] pyrrole derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2021-02-05 | — | — | CN | disclosed |
| WO-2012085935-A2 | COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2012-06-28 | — | — | WO | disclosed |
| US-20090209520-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2009-08-20 | — | — | US | disclosed |
| US-20090209520-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2009-08-20 | — | — | US | disclosed |
| US-20090209520-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2009-08-20 | — | — | US | disclosed |
| CN-101484421-A | 2-oxybenzamide derivatives as PARP inhibitors | KUDOS PHARM LTD (GB) | 2009-07-15 | — | — | CN | disclosed |
| EP-2041087-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | Kudos Pharmaceuticals Limited (GB) | 2009-04-01 | — | — | EP | disclosed |
| WO-2007144639-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144639-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209520-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | PARP2, PARP3, PARP12 | RARB 3946/4885RARA 4170/4885RARG 4418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.