SCHEMBL5428211

SCHEMBL5428211

CN(C=Cc1ccccc1)C=Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.54
MAOB P27338 2/20 0.50
GRM5 P41594 1/20 0.47
CHAT P28329 2/20 0.44
HTR2A P28223 3/20 0.43
TRPA1 O75762 2/20 0.43
GLA P06280 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NFE2L2 Q16236 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
ALOX5 P09917 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5428210 1.00 RELA (0.54) RELAMAOBGRM5CHATHTR2A
SCHEMBL19570278 0.86 RELA (0.47) RELAMAOBGRM5CHATHTR2A
SCHEMBL952396 0.84 RELA (0.54) RELAMAOBGRM5CHATTRPA1
SCHEMBL81307 0.84 RELA (0.54) RELAMAOBGRM5CHATTRPA1
Hydrochloric Acid SCHEMBL9225053 0.82 RELA (0.52) RELAMAOBGRM5CHATTRPA1
Water SCHEMBL27350733 0.82 RELA (0.52) RELAMAOBGRM5CHATTRPA1
(Z)-1,2-Diphenylethene SCHEMBL27459562 0.80 RELA (0.68) RELAMAOBGRM5CHATTRPA1
SCHEMBL28708571 0.80 RELA (0.50) RELAMAOBGRM5CHATTRPA1
SCHEMBL10628459 0.78 RELA (0.54) RELAMAOBGRM5CHATTRPA1
SCHEMBL168457 0.78 MAOB (0.55) RELAMAOBCHATTRPA1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070155636-A1 Lubricating oil additive and lubricating oil composition containing the same ADEKA CORPORATION (JP) 2007-07-05 US disclosed
EP-1717298-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION CONTAINING SAME Adeka Corporation (JP) 2006-11-02 EP disclosed