Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | CHAT | P28329 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81307 | 1.00 | RELA (0.54) | RELAMAOBGRM5CHATRECQL | |
| Hydrochloric Acid SCHEMBL9225053 | 0.97 | RELA (0.52) | RELAMAOBGRM5CHATRECQL | |
| Water SCHEMBL27350733 | 0.97 | RELA (0.52) | RELAMAOBGRM5CHATRECQL | |
| Ethylene Glycol SCHEMBL28698002 | 0.89 | RELA (0.45) | RELAMAOBGRM5CHATRECQL | |
| Styrene SCHEMBL26089496 | 0.89 | ALDH1A1 (0.58) | RELAMAOBGRM5CHATRECQL | |
| SCHEMBL4993147 | 0.85 | ALDH1A1 (0.43) | RELAMAOBGRM5CHATRECQL | |
| SCHEMBL5428211 | 0.84 | RELA (0.54) | RELAMAOBGRM5CHATTRPA1 | |
| SCHEMBL5428210 | 0.84 | RELA (0.54) | RELAMAOBGRM5CHATTRPA1 | |
| Benzoic Acid SCHEMBL29066270 | 0.84 | RECQL (0.55) | MAOBRECQLGLATDP1ALDH1A1 | |
| SCHEMBL27964093 | 0.83 | MAOB (0.64) | RELAMAOBGRM5CHATRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57028046-A | — | — | None | — | — | JP | disclosed |
| US-11773052-B2 | Enamine compound and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2023-10-03 | — | — | US | disclosed |
| EP-2729463-B1 | SUBSTITUTED PHENYL COMPOUNDS | SANOFI SA (FR) | 2015-07-29 | — | — | EP | disclosed |
| US-8785642-B2 | Process for preparing 6-substituted-1-(2H)-isoquinolinones and intermediate compound | SANOFI (FR) | 2014-07-22 | — | — | US | disclosed |
| EP-2729463-A1 | SUBSTITUTED PHENYL COMPOUNDS | SANOFI (FR) | 2014-05-14 | — | — | EP | disclosed |
| US-8716481-B2 | Process for the preparation of 6-substituted-1-(2H)-isoquinolinones | SANOFI (FR) | 2014-05-06 | — | — | US | disclosed |
| WO-2013007502-A1 | SUBSTITUTED PHENYL COMPOUNDS | SANOFI (FR) | 2013-01-17 | — | — | WO | disclosed |
| US-20130012711-A1 | SUBSTITUTED PHENYL COMPOUNDS | SANOFI (FR) | 2013-01-10 | — | — | US | disclosed |
| US-20110021779-A1 | PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES | SANOFI-AVENTIS (FR) | 2011-01-27 | — | — | US | disclosed |
| EP-2240441-A1 | PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES | Sanofi-Aventis (FR) | 2010-10-20 | — | — | EP | disclosed |
| EP-1178040-A1 | Nickel catalyzed addition of -NH- containing compounds to vinyl and aryl halides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-1065934-A1 | COMBINATION OF GLYPHOSATE AND A TRIAZOLINONE HERBICIDE | MONSANTO COMPANY (US) | 2001-01-10 | — | — | EP | disclosed |
| US-6127318-A | POSTEMERGENT HERBICIDE MIXTURE ALLOWS RAPID UPTAKE BY THE TARGET PLANT, EARLY VISUAL SYMPTOMS OF PLANT TREATMENT, AND CONTROL OF A BROAD SPECTRUM OF WEED SPECIES | MONSANTO COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| US-6103937-A | PRODUCING UNSATURATED NITROGEN CONTAINING COMPOUNDS SUCH AS ENAMIDES, ENAMINES AND ARYL AMINESLAMIDES USING AS CATALYST NICKEL AND AN ORGANOPHOSPHINE OR CARBENE LIGAND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| WO-1999051099-A1 | COMBINATION OF GLYPHOSATE AND A TRIAZOLINONE HERBICIDE | MONSANTO COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |
| EP-0912510-A1 | NICKEL CATALYZED ADDITION OF -NH- CONTAINING COMPOUNDS TO VINYL AND ARYL HALIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000399-A1 | NICKEL CATALYZED ADDITION OF -NH- CONTAINING COMPOUNDS TO VINYL AND ARYL HALIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-01-08 | — | — | WO | disclosed |
| JP-S5728046-A | PREPARATION OF 4-SUBSTITUTED INDOLE | NISSAN CHEM IND LTD | 1982-02-15 | — | — | JP | disclosed |
| US-4082768-A | NEW IMIDES OF UNSATURATED DICARBOXYLIC ACIDS, PROCESSES FOR THEIR MANUFACTURE, AND THEIR USE | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
| US-3960812-A | DIELECTRICS, MECHANICAL PROPERTIES | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021779-A1 | PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES | CYP1B1, CYP1A1, NQO1 | RELA 404/4885MAOB 296/4885GRM5 2534/4885 |
| US-11773052-B2 | Enamine compound and use thereof | ENY2, AHR, PAH | RELA 1904/4885MAOB 35/4885GRM5 1245/4885 |
| US-20130012711-A1 | SUBSTITUTED PHENYL COMPOUNDS | PAH, NQO1, CYP1B1 | RELA 330/4885MAOB 96/4885GRM5 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.