Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.66 |
| ▸ | EGLN3 | Q9H6Z9 | 6/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.46 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.44 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.44 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.44 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.44 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238459 | 0.89 | EGLN1 (0.67) | EGLN1EGLN3EGLN2HIF1AKDM4E | |
| SCHEMBL8247149 | 0.85 | EGLN1 (0.73) | EGLN1EGLN3EGLN2HIF1AKDM4E | |
| SCHEMBL8244112 | 0.80 | EGLN1 (0.57) | EGLN1EGLN3EGLN2HIF1AKDM4E | |
| SCHEMBL8244419 | 0.80 | EGLN1 (1.00) | EGLN1EGLN3EGLN2HIF1AKDM4E | |
| SCHEMBL5307125 | 0.79 | EGLN1 (0.61) | EGLN1EGLN3EGLN2HIF1AKDM4E | |
| SCHEMBL8238447 | 0.79 | EGLN1 (0.70) | EGLN1EGLN3EGLN2HIF1AKDM4E | |
| SCHEMBL8247257 | 0.78 | EGLN1 (0.60) | EGLN1EGLN3EGLN2HIF1AKDM4E | |
| SCHEMBL8247158 | 0.78 | EGLN1 (0.52) | EGLN1EGLN3EGLN2HIF1AMEN1 | |
| SCHEMBL2761583 | 0.77 | EDNRA (0.48) | EGLN1 | |
| SCHEMBL8250095 | 0.77 | EGLN1 (0.70) | EGLN1EGLN3EGLN2HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |