Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742611 | 1.00 | MEN1 (0.42) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL8089082 | 1.00 | MEN1 (0.42) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL5432123 | 0.85 | MEN1 (0.41) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL13360951 | 0.85 | KMT2A (0.41) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL8088306 | 0.82 | KMT2A (0.39) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL13330960 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL29675255 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL3312164 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL22380433 | 0.80 | APLNR (0.40) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL22482737 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | CHRM1, CHRNA1, CHRNA9 | MEN1 2822/4885MAPK1 2352/4885KMT2A 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.