Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742611 | 1.00 | MEN1 (0.42) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL5428985 | 1.00 | MEN1 (0.42) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL5432123 | 0.85 | MEN1 (0.41) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL13360951 | 0.85 | KMT2A (0.41) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL8088306 | 0.82 | KMT2A (0.39) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL13330960 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL29675255 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL3312164 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL22380433 | 0.80 | APLNR (0.40) | MEN1MAPK1KMT2ATDP1CACNA1H | |
| SCHEMBL22482737 | 0.80 | MEN1 (0.38) | MEN1MAPK1KMT2ATDP1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009008913-A2 | P1-NONEPIMERIZABLE KETOAMIDE INHIBITORS OF HCV NS3 PROTEASE | SCHERING CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |