SCHEMBL542901

SCHEMBL542901

CC(C)(C)OOOC(=O)OC(=O)OOOC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL31265746 0.95 TSHR (0.32) TSHRTDP1ALDH1A1HSD17B10
Ethylene SCHEMBL31265739 0.95 TSHR (0.32) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL1899001 0.89 TSHR (0.39) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL542902 0.88 TSHR (0.35) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL28601550 0.86 TSHR (0.37) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL9862963 0.85 TSHR (0.33) TSHR
SCHEMBL9752398 0.84 HSD17B10 (0.41) TDP1HSD17B10
SCHEMBL21753800 0.84 TSHR (0.35) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL42540 0.83 TSHR (0.41) TSHRTDP1ALDH1A1HSD17B10SOAT1
SCHEMBL17727755 0.82 ELANE (0.35) TSHRTDP1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3779572-B1 OPTICAL ARTICLE HOYA LENS THAILAND LTD (TH) 2025-11-19 EP disclosed
EP-3682862-B1 CURABLE DENTAL COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-11-20 EP disclosed
US-11958970-B2 Dental cut processing resin-based block TOKUYAMA DENTAL CORPORATION (JP) 2024-04-16 US disclosed
US-11709337-B2 Optical article HOYA LENS THAILAND LTD. (TH) 2023-07-25 US disclosed
CN-113840590-B Dental cutting material and method for manufacturing same 株式会社德山齿科 2023-04-18 CN disclosed
US-11526031-B2 Optical article HOYA LENS THAILAND LTD. (TH) 2022-12-13 US disclosed
US-11452675-B2 Dental curable composition TOKUYAMA DENTAL CORPORATION (JP) 2022-09-27 US disclosed
CN-113840590-A Dental cutting material and method for manufacturing same 株式会社德山齿科 2021-12-24 CN disclosed
US-20210095113-A1 DENTAL CUT PROCESSING RESIN-BASED BLOCK TOKUYAMA DENTAL CORPORATION (JP) 2021-04-01 US disclosed
EP-3779572-A1 OPTICAL ARTICLE Hoya Lens Thailand Ltd. (TH) 2021-02-17 EP disclosed
EP-1359170-A1 PHOTOCHROMIC CURABLE COMPOSITION AND CURED ARTICLES THEREOF TOKUYAMA CORPORATION (JP) 2003-11-05 EP disclosed
US-20030162863-A1 Photo-curable reparative material for dental use TOKUYAMA CORPORATION (JP) 2003-08-28 US disclosed
US-20030096117-A1 Chromene compound TOKUYAMA CORPORATION (JP) 2003-05-22 US disclosed
EP-1291388-A1 CURABLE COMPOSITION AND PHOTOCHROMIC CURED ARTICLE TOKUYAMA CORPORATION (JP) 2003-03-12 EP disclosed
US-20030036582-A1 Dental curable composition TOKUYAMA CORPORATION (JP) 2003-02-20 US disclosed
US-20030008958-A1 Curable composition and photochromic cured article TOKUYAMA CORPORATION (JP) 2003-01-09 US disclosed
EP-1236459-A1 PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2002-09-04 EP disclosed
EP-1226807-A1 DENTAL CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2002-07-31 EP disclosed
EP-1184379-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2002-03-06 EP disclosed
EP-1130038-A1 CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2001-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11452675-B2 Dental curable composition SP1, H1-0, ERH TSHR 2781/4885TDP1 1761/4885ALDH1A1 1047/4885
US-20030162863-A1 Photo-curable reparative material for dental use MBTD1, AP3M1, MYO1G TSHR 3616/4885TDP1 1404/4885ALDH1A1 1806/4885
US-20030096117-A1 Chromene compound SMARCE1, SMARCD2, SMARCB1 TSHR 3797/4885TDP1 2311/4885ALDH1A1 3101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.