Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.82 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 4/20 | 0.57 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL41629 | 1.00 | — | — | |
| Acetic Acid SCHEMBL11533245 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL12983374 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL6749539 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL437034 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL11168446 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL6856161 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL11171825 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL7316954 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL10939984 | 1.00 | CA1 (0.82) | CA1FFAR3LCKFYNCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066767-A1 | Polyalkylene glycols | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| US-6746684-B2 | CORE COATED WITH A RESIN WALL MATERIAL FORMED BY WATER-SOLUBLE MELAMINE-FORMALDEHYDE RESIN TO POLYCONDENSATION IN A DISPERSANT OF CONDENSATION PRODUCT OF (ALKYL)NAPHTHALENE-SULFONIC ACID AND FORMALDEHYDE | SYNGENTA CROP PROTECTION, INC. | 2004-06-08 | — | — | US | disclosed |
| EP-1170997-B1 | MICROENCAPSULATED SOLID PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-20020081337-A1 | Microencapsulated solid pesticides | MERRILL LYNCH CAPITAL, A DIVISION OF MERRILL LYNCH | 2002-06-27 | — | — | US | disclosed |
| EP-1170997-A1 | MICROENCAPSULATED SOLID PESTICIDES | Syngenta Participations AG (CH) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000062612-A1 | MICROENCAPSULATED SOLID PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066767-A1 | Polyalkylene glycols | PUF60, PARG, DGAT1 | CA1 2421/4885FFAR3 1282/4885LCK 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.