Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 3/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.52 |
| ▸ | PRKACA | P17612 | 2/20 | 0.52 |
| ▸ | PRKACG | P22612 | 2/20 | 0.52 |
| ▸ | PRKACB | P22694 | 2/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.52 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Fluorocamalexin SCHEMBL12993647 | 0.82 | MAP3K14 (0.52) | PIM1HTR1AHTR7HTR6HTR2A | |
| 5-Methoxycamalexin SCHEMBL12993651 | 0.79 | MAP3K14 (0.55) | GSK3BCYP1A2HTR1AHTR7HTR6 | |
| Camalexin SCHEMBL343413 | 0.78 | HSD17B10 (0.51) | CLK1CDK5CDK5R1CDK1CCNB1 | |
| SCHEMBL5429556 | 0.77 | GPR84 (0.62) | CLK1CDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL22591300 | 0.76 | GPR84 (0.46) | CLK1CDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL4290310 | 0.75 | FLT3 (0.56) | CDK5PRKACACSNK1A1CSNK1DGSK3B | |
| 6-Fluorocamalexin SCHEMBL12993648 | 0.73 | TDO2 (0.55) | GPR84 | |
| SCHEMBL22591375 | 0.73 | GPR84 (0.44) | CLK1CDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL25034344 | 0.72 | MEN1 (0.60) | CLK1CDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL11757620 | 0.72 | PIM1 (0.60) | CLK1CDK5CDK5R1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380815-B | Plant protection camalexin derivative and preparation method and application thereof | 河北工业大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-114380815-A | Phytoalexin derivative and preparation method and application thereof | 河北工业大学 | 2022-04-22 | — | — | CN | disclosed |
| US-20070149514-A1 | Indole-phenylsulfonamide derivatives used as ppar-delta activating compounds | BAYER HEALTHCARE AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-20070149514-A1 | Indole-phenylsulfonamide derivatives used as ppar-delta activating compounds | BAYER HEALTHCARE AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-20070149514-A1 | Indole-phenylsulfonamide derivatives used as ppar-delta activating compounds | BAYER HEALTHCARE AG (DE) | 2007-06-28 | — | — | US | disclosed |
| EP-1583743-A1 | INDOLE-PHENYLSULFONAMIDE DERIVATIVES USED AS PPAR-DELTA ACTIVATING COMPOUNDS | Bayer HealthCare AG (DE) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004060871-A1 | INDOLE-PHENYLSULFONAMIDE DERIVATIVES USED AS PPAR-DELTA ACTIVATING COMPOUNDS | BAYER HEALTHCARE AG (DE) | 2004-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149514-A1 | Indole-phenylsulfonamide derivatives used as ppar-delta activating compounds | PPARD, PPARA, PPARG | CLK1 2036/4885CDK5 1059/4885CDK5R1 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.