Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431557 | 0.79 | CHRNA7 (0.53) | LSSCHRNA7CHRM2CHRM1CHRM3 | |
| Trifluoroacetic Acid SCHEMBL5412775 | 0.76 | LSS (0.44) | LSSCHRNA7CHRM2CHRM1CHRM3 | |
| SCHEMBL5650196 | 0.71 | LSS (0.49) | LSSCHRNA7CHRM2CHRM1CHRM3 | |
| Trifluoroacetic Acid SCHEMBL5412769 | 0.70 | LSS (0.44) | LSSCHRNA7 | |
| SCHEMBL5417690 | 0.70 | CHRNA7 (0.45) | LSSCHRNA7CHRM1 | |
| SCHEMBL5408455 | 0.69 | CHRNA7 (0.53) | LSSCHRNA7CHRM2CHRM1CHRM3 | |
| SCHEMBL5420568 | 0.68 | CHRM2 (0.50) | LSSCHRNA7CHRM2CHRM1CHRM3 | |
| Fumaric Acid SCHEMBL5417070 | 0.68 | LSS (0.50) | LSSCHRNA7CHRM2CHRM1CHRM3 | |
| Fumaric Acid SCHEMBL5417065 | 0.68 | LSS (0.50) | LSSCHRNA7CHRM2CHRM1CHRM3 | |
| Trifluoroacetic Acid SCHEMBL5407597 | 0.68 | CHRNA7 (0.53) | LSSCHRNA7CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275975-A1 | 3-QUINUCLIDINYL AMINO-SUBSTITUTED BIARYL DERIVATIVES | JI JIANGUO | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275975-A1 | 3-QUINUCLIDINYL AMINO-SUBSTITUTED BIARYL DERIVATIVES | CHRNA7, CHRNA9, CHRNA1 | LSS 2291/4885CHRNA7 1/4885CHRM2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.