SCHEMBL5430673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8023222	0.92	PTGS2 (0.85)	PTGS2PDPK1PTGESHDAC3CA12
	SCHEMBL8034991	0.91	PTGS2 (0.83)	PTGS2
	SCHEMBL8033137	0.90	PTGS2 (0.82)	PTGS2
	SCHEMBL8032904	0.90	PTGS2 (1.00)	PTGS2PTGS1
	SCHEMBL8032915	0.90	PTGS2 (0.96)	PTGS2PDPK1PTGS1
	SCHEMBL8023242	0.90	PTGS2 (1.00)	PTGS2PDPK1PTGS1
	SCHEMBL8023535	0.89	PTGS2 (0.80)	PTGS2PTGS1
	SCHEMBL8039820	0.89	PTGS2 (1.00)	PTGS2PTGS1
	SCHEMBL8033447	0.89	PTGS2 (0.80)	PTGS2PTGS1
	SCHEMBL8034704	0.89	PTGS2 (1.00)	PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.