Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305460 | 0.86 | ALDH1A1 (0.41) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL542859 | 0.81 | MEN1 (0.40) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL15873778 | 0.81 | PLCG1 (0.44) | ALDH1A1MAPK1CA1CA2CA12 | |
| SCHEMBL542839 | 0.81 | GAA (0.43) | ALDH1A1CYP3A4CA1CA2CA12 | |
| SCHEMBL6259970 | 0.79 | PKM (0.50) | ALDH1A1CA1CA2TDP1MMP2 | |
| SCHEMBL6338672 | 0.78 | KCNH2 (0.46) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL6115151 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL11133439 | 0.77 | STAT3 (0.40) | ALDH1A1CYP3A4CA1CA2CA12 | |
| SCHEMBL11291803 | 0.75 | POLB (0.49) | ALDH1A1MAPK1CA2CA12CA9 | |
| SCHEMBL22320275 | 0.75 | POLB (0.49) | ALDH1A1MAPK1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8529682-B2 | Process for preparing an indicator composition and indicator compositions | TEMPTIME CORPORATION (US) | 2013-09-10 | — | — | US | claimed |
| EP-1048476-B1 | Time-temperature medium and use | NCR INT INC (US) | 2005-10-12 | — | — | EP | claimed |
| US-6524000-B1 | A recording material comprising a base sheet suitable for feeding into a thermal printer, wherein said thermal printer is suitable for generating a thermal image on thermal paper, | NCR CORPORATION | 2003-02-25 | — | — | US | claimed |
| US-6517239-B1 | Time-temperature indicators activated with thermal transfer printing and methods for their production | NCR CORPROATION | 2003-02-11 | — | — | US | claimed |
| EP-1048477-A1 | Time-temperature indicators activated with direct thermal printing and methods for their production | NCR INTERNATIONAL INC. (US) | 2000-11-02 | — | — | EP | claimed |
| EP-1048476-A1 | Time-temperature indicators activated with thermal transfer printing and methods for their production | NCR INTERNATIONAL INC. (US) | 2000-11-02 | — | — | EP | claimed |
| US-4298348-A | 2,4-HEXADIYN-1,6-DIOL-BIS(P-CHLOROBENZENESULFONATE) ON A SUBSTRATE | ALLIED CORPORATION (US) | 1981-11-03 | — | — | US | claimed |
| US-20190137462-A1 | A TIME-TEMPERATURE INDICATOR BASED ON INCREASED THERMAL REACTIVITY OF A DIACETYLENE UPON MELT RECRYSTALLIZATION | JP LABORATORIES INC. | 2019-05-09 | — | — | US | disclosed |
| EP-3452822-A1 | A TIME-TEMPERATURE INDICATOR BASED ON INCREASED THERMAL REACTIVITY OF A DIACETYLENE UPON MELT RECRYSTALLIZATION | JP Laboratories (US) | 2019-03-13 | — | — | EP | disclosed |
| US-20180100807-A1 | COLOR-CHANGING ENVIRONMENTAL STIMULUS INDICATOR WITH REFERENCE OF VARIABLE APPEARANCE | TEMPTIME CORPORATION (US) | 2018-04-12 | — | — | US | disclosed |
| WO-2017192444-A1 | A TIME-TEMPERATURE INDICATOR BASED ON INCREASED THERMAL REACTIVITY OF A DIACETYLENE UPON MELT RECRYSTALLIZATION | JP LABORATORIES (US) | 2017-11-09 | — | — | WO | disclosed |
| EP-2414420-B1 | CO-CRYSTALLIZABLE DIACETYLENIC MONOMER COMPOSITIONS, CRYSTAL PHASES AND MIXTURES, AND RELATED METHODS | TEMPTIME CORP (US) | 2015-07-08 | — | — | EP | disclosed |
| US-20130239874-A1 | ROBUST, ULTRAVIOLET-PROTECTED AMBIENT CONDITION HISTORY INDICATOR AND METHOD OF MAKING SAME | TEMPTIME CORPORATION (US) | 2013-09-19 | — | — | US | disclosed |
| US-6524000-B1 | A recording material comprising a base sheet suitable for feeding into a thermal printer, wherein said thermal printer is suitable for generating a thermal image on thermal paper, | NCR CORPORATION | 2003-02-25 | — | — | US | disclosed |
| US-6517239-B1 | Time-temperature indicators activated with thermal transfer printing and methods for their production | NCR CORPROATION | 2003-02-11 | — | — | US | disclosed |
| EP-1048477-A1 | Time-temperature indicators activated with direct thermal printing and methods for their production | NCR INTERNATIONAL INC. (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-1048476-A1 | Time-temperature indicators activated with thermal transfer printing and methods for their production | NCR INTERNATIONAL INC. (US) | 2000-11-02 | — | — | EP | disclosed |
| US-4298348-A | 2,4-HEXADIYN-1,6-DIOL-BIS(P-CHLOROBENZENESULFONATE) ON A SUBSTRATE | ALLIED CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |
| US-4298348-A | 2,4-HEXADIYN-1,6-DIOL-BIS(P-CHLOROBENZENESULFONATE) ON A SUBSTRATE | ALLIED CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |
| US-4278561-A | MONITORING SHELF LIFE OF PERISHABLES, POLYMERIZATION, COLOR CHANGE | ALLIED CHEMICAL CORPORATION (US) | 1981-07-14 | — | — | US | disclosed |