Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30735542 | 0.90 | IAPP (0.58) | IAPPTLR8PTGER1PTGER4PTGER3 | |
| SCHEMBL5440713 | 0.85 | CYSLTR2 (0.48) | IAPPCYSLTR2CYSLTR1KDM4EMAPT | |
| SCHEMBL4320084 | 0.84 | GABRA1 (0.50) | IAPPTLR8PTGER1PTGER4PTGER3 | |
| SCHEMBL5431849 | 0.83 | IAPP (0.46) | IAPPPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8206128 | 0.82 | TLR8 (0.51) | TLR8PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3415700 | 0.82 | CA2 (0.50) | IAPPTLR8ABL1ABCB1BCR | |
| SCHEMBL3415698 | 0.82 | CA2 (0.50) | IAPPTLR8ABL1ABCB1BCR | |
| SCHEMBL30337793 | 0.82 | CA2 (0.50) | IAPPTLR8ABL1ABCB1BCR | |
| SCHEMBL8409600 | 0.81 | IAPP (0.47) | IAPPCYSLTR2CYSLTR1PDE5AERN1 | |
| SCHEMBL8409598 | 0.81 | IAPP (0.47) | IAPPCYSLTR2CYSLTR1PDE5AERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191540-A1 | LOW DIELECTRIC LOSS RESIN, RESIN COMPOSITION, AND THE MANUFACTURING METHOD OF LOW DIELECTRIC LOSS RESIN | HITACHI, LTD. (JP) | 2007-08-16 | — | — | US | disclosed |