SCHEMBL543138

SCHEMBL543138

O=C=Nc1ccc2c(c1)Cc1cc(N=C=O)ccc1-2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP3A4 P08684 5/20 0.46
TRPA1 O75762 1/20 0.46
TSHR P16473 1/20 0.42
RAB9A P51151 4/20 0.38
MAPT P10636 3/20 0.38
NPC1 O15118 2/20 0.38
CYP1A2 P05177 6/20 0.37
ALDH1A1 P00352 3/20 0.37
CYP2C19 P33261 2/20 0.37
CYP2C9 P11712 2/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
CASP6 P55212 1/20 0.35
GFER P55789 1/20 0.35
PNMT P11086 1/20 0.35
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9232010 0.94 MAPK1 (0.44) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL672776 0.91 CYP1A2 (0.49) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL29648833 0.91 CYP1A2 (0.49) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL28651125 0.89 METAP1 (0.44) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL11231604 0.88 MAPK1 (0.48) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL9354209 0.84 TLR9 (0.57) MAPK1TDP1CYP3A4RAB9AMAPT
SCHEMBL9778379 0.83 MAPT (0.38) MAPK1TDP1CYP3A4TRPA1RAB9A
SCHEMBL1169190 0.81 CYP3A4 (0.41) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL12911060 0.78 KMT2A (0.48) MAPK1TDP1CYP3A4RAB9AMAPT
SCHEMBL28448245 0.78 TDP1 (0.56) MAPK1TDP1CYP3A4TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10570561-B2 Sizing agent for carbon fiber, carbon fiber with improved interfacial adhesion, polymerization reaction type carbon fiber-reinforced polymer composite material using same, and production method therefor KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2020-02-25 US claimed
US-20190284751-A1 SIZING AGENT FOR CARBON FIBER, CARBON FIBER WITH IMPROVED INTERFACIAL ADHESION, POLYMERIZATION REACTION TYPE CARBON FIBER-REINFORCED POLYMER COMPOSITE MATERIAL USING SAME, AND PRODUCTION METHOD THEREFOR KOREA INSTITUTE OF MATERIALS SCIENCE (KR) 2019-09-19 US claimed
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
CN-118046659-A Lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2024-05-17 CN disclosed
CN-114072290-B On-press development type lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2024-04-30 CN disclosed
EP-4349602-A2 ORIGINAL PLATE FOR ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE, METHOD FOR FABRICATING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM Corporation (JP) 2024-04-10 EP disclosed
CN-114450161-B Lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2024-04-02 CN disclosed
CN-114531860-B Lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2024-01-30 CN disclosed
CN-114126889-B Lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2024-01-26 CN disclosed
US-11874602-B2 Lithographic printing plate precursor, method for preparing lithographic printing plate, and lithographic printing method FUJIFILM CORPORATION (JP) 2024-01-16 US disclosed
CN-114051454-B On-press development type lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2023-12-15 CN disclosed
US-4136238-A FROM WATER GLASS AND DIISOCYANATES METALLGESELLSCHAFT A.G. (DE) 1979-01-23 US disclosed
US-4125693-A Process for the production of polyurethanes dissolved in a solvent and also their use for the production of fabricated shapes, especially of microporous structures CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-11-14 US disclosed
US-4123599-A PHENOLIC RESINS REACTED WITH ORGANIC DIISOCYANATES AND/OR POLYISOCYANTES IN THE PRESENCE OF METAL POWDERS AND/OR METAL OXIDE POWDERS CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-10-31 US disclosed
US-4108807-A REACTING A METALLATE WITH A PSEUDOHALIDE IN THE PRESENCE OF A PHENOL-SUBSTITUTED TERTIARY AMINE CATALYST CHEMIC-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-08-22 US disclosed
US-4108954-A Process of producing shaped structures of crosslinked elastomeric polyurethane CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-08-22 US disclosed
US-4098730-A Non-flammable organo-red mud polymers, some of which are electrically conductive, and process for their manufacture METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) 1978-07-04 US disclosed
US-4031035-A Polyurethane-amide resins based upon isocyanate terminated prepolymers of bis-(2-hydroxyethyl)terephthalate CELANESE CORPORATION (US) 1977-06-21 US disclosed
US-3969394-A Polyurethanes CELANESE CORPORATION (US) 1976-07-13 US disclosed
US-3931065-A POLYURETHANE-MODIFIED POLYISOCYANURATE FOAM AND A METHOD FOR THE PREPARATION THEREOF NISSHIN BOSEKI KABUSHIKI KAISHA (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570561-B2 Sizing agent for carbon fiber, carbon fiber with improved interfacial adhesion, polymerization reaction type carbon fiber-reinforced polymer composite material using same, and production method therefor NOTUM, MACF1, FAR1 MAPK1 2074/4885TDP1 3316/4885CYP3A4 796/4885
US-20190284751-A1 SIZING AGENT FOR CARBON FIBER, CARBON FIBER WITH IMPROVED INTERFACIAL ADHESION, POLYMERIZATION REACTION TYPE CARBON FIBER-REINFORCED POLYMER COMPOSITE MATERIAL USING SAME, AND PRODUCTION METHOD THEREFOR NOTUM, MACF1, FAR1 MAPK1 2074/4885TDP1 3316/4885CYP3A4 796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.