Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.82 |
| ▸ | HTR1A | P08908 | 3/20 | 0.63 |
| ▸ | HTR1B | P28222 | 3/20 | 0.63 |
| ▸ | HTR2C | P28335 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | HTR1D | P28221 | 2/20 | 0.63 |
| ▸ | HTR5A | P47898 | 2/20 | 0.63 |
| ▸ | HTR6 | P50406 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432125 | 0.91 | HTR7 (0.70) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL4797436 | 0.91 | HTR7 (1.00) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL5929995 | 0.91 | HTR7 (0.74) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL38652005 | 0.91 | HTR7 (0.74) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL5424833 | 0.90 | HTR7 (0.72) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL4348714 | 0.89 | HTR7 (0.72) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| Hydrochloric Acid SCHEMBL9448770 | 0.89 | HTR7 (0.97) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL8297284 | 0.88 | HTR7 (0.70) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL3347386 | 0.88 | HTR7 (0.70) | HTR7HTR1AHTR1BHTR2CHSD17B10 | |
| SCHEMBL9256337 | 0.88 | HTR7 (0.70) | HTR7HTR1AHTR1BHTR2CHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015813-A1 | Treatment of protein folding disorders | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-01-18 | — | — | US | claimed |
| US-20070015813-A1 | Treatment of protein folding disorders | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015813-A1 | Treatment of protein folding disorders | HSPA5, TTR, TUFM | HTR7 1505/4885HTR1A 710/4885HTR1B 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.