Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 8/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429317 | 0.87 | CNR1 (0.53) | CNR1CNR2ACHESSTR4ROCK2 | |
| SCHEMBL8719218 | 0.87 | CNR1 (0.53) | CNR1CNR2ACHESSTR4ROCK2 | |
| SCHEMBL5433258 | 0.86 | CNR1 (0.57) | CNR1CNR2ACHESSTR4PADI4 | |
| SCHEMBL31429457 | 0.82 | CNR1 (0.54) | CNR1CNR2ACHESSTR4ROCK2 | |
| SCHEMBL24437187 | 0.82 | CNR1 (0.56) | CNR1CNR2ACHESSTR4ROCK2 | |
| SCHEMBL31429426 | 0.82 | CNR1 (0.56) | CNR1CNR2ACHESSTR4ROCK2 | |
| SCHEMBL4052657 | 0.81 | CNR1 (0.61) | CNR1CNR2ACHESSTR4ROCK2 | |
| SCHEMBL6950019 | 0.79 | CYP1A2 (0.45) | CNR1CNR2SSTR4HTR3ACYP1A2 | |
| SCHEMBL15882181 | 0.79 | HTR4 (0.48) | CNR1CNR2ACHEROCK2HTR4 | |
| SCHEMBL31429308 | 0.79 | HTR4 (0.48) | CNR1CNR2ACHEROCK2HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |