SCHEMBL31429317

SCHEMBL31429317

O=C(O)c1nn(CC2CC2)c2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.53
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
TSHR P16473 1/20 0.51
PMP22 Q01453 1/20 0.51
HIF1A Q16665 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ACHE P22303 1/20 0.48
CNR2 P34972 1/20 0.48
SSTR4 P31391 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ROCK2 O75116 3/20 0.45
PTGER4 P35408 2/20 0.43
USP30 Q70CQ3 1/20 0.43
HTR4 Q13639 1/20 0.42
HTR3A P46098 2/20 0.42
KDM4C Q9H3R0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8719218 1.00 CNR1 (0.53) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31429426 0.94 CNR1 (0.56) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL24437187 0.94 CNR1 (0.56) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4052657 0.93 CNR1 (0.61) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15882181 0.91 HTR4 (0.48) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31429308 0.91 HTR4 (0.48) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15897922 0.87 CYP1A2 (0.48) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5433258 0.87 CNR1 (0.57) CNR1ACHECNR2SSTR4PADI4
SCHEMBL8713428 0.87 CNR1 (0.52) CNR1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15882309 0.86 ROCK1 (0.52) CNR1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092014-A1 COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE METREA BIOSCIENCES INC (US) 2025-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092014-A1 COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE LPL, LIPA, PNLIP CNR1 3940/4885CYP1A2 973/4885CYP3A4 896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.