Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779432 | 0.96 | CYP3A4 (0.51) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL11085613 | 0.86 | TSHR (0.56) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL27654343 | 0.85 | TSHR (0.49) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL18314787 | 0.83 | ATM (0.49) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL14028176 | 0.82 | DGKA (0.43) | ALDH1A1DGKALMNAEPHX2HTR2C | |
| SCHEMBL29489877 | 0.82 | TSHR (0.64) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL28642580 | 0.81 | DGKA (0.46) | ALDH1A1DGKALMNAEPHX2HTR2C | |
| SCHEMBL27000290 | 0.81 | CYP3A4 (0.49) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL13659026 | 0.81 | DGKA (0.55) | TSHRATMALDH1A1DGKALMNA | |
| SCHEMBL9719720 | 0.80 | TSHR (0.60) | TSHRCYP3A4ATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725520-A2 | FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLIGICAL PREPARATIONS | MERCK PATENT GmbH (DE) | 2006-11-29 | — | — | EP | claimed |
| WO-2005074897-A2 | FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLOGICAL PREPARATIONS | MERCK PATENT GMBH (DE) | 2005-08-18 | — | — | WO | claimed |
| US-20070141014-A1 | Formulation assistants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070141014-A1 | Formulation assistants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070141014-A1 | Formulation assistants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-06-21 | — | — | US | disclosed |
| EP-1725520-A2 | FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLIGICAL PREPARATIONS | MERCK PATENT GmbH (DE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005074897-A2 | FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLOGICAL PREPARATIONS | MERCK PATENT GMBH (DE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141014-A1 | Formulation assistants | C1S, C1R, AKR1C3 | TSHR 2444/4885CYP3A4 104/4885ATM 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.