SCHEMBL54336

SCHEMBL54336

CNC(=O)C(=NOC)c1ccccc1COc1cc(C)ccc1C

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.49
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2866788 1.00 HIF1A (0.49) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL29673995 1.00 HIF1A (0.49) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL22326129 1.00 HIF1A (0.49) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL31349879 1.00 HIF1A (0.49) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL18420 1.00 HIF1A (0.49) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL8370193 0.91 HIF1A (0.50) HIF1ATDP1LMNAPOLB
SCHEMBL8370194 0.91 HIF1A (0.50) HIF1ATDP1LMNAPOLB
SCHEMBL8397931 0.91 HIF1A (0.50) HIF1ATDP1LMNAPOLB
SCHEMBL7539663 0.90 HIF1A (0.48) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL27389817 0.90 HIF1A (0.48) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
EP-4161273-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2023-04-12 EP claimed
EP-4161277-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2023-04-12 EP claimed
EP-3644743-B1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2022-10-26 EP claimed
WO-2021244951-A9 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-01-13 WO claimed
CN-111107745-B Fungicidal compositions 先正达参股股份有限公司 2021-12-07 CN claimed
EP-3582616-B1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2020-12-16 EP claimed
EP-3518675-B1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2020-08-19 EP claimed
WO-2018219773-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2018-12-06 WO claimed
WO-2018177880-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2018-10-04 WO claimed
US-20010046978-A1 Synergistic fungicidal composition comprising a compound analogous to strobilurin DUVERT PATRICE (FR) 2001-11-29 US claimed
EP-0836385-B1 CROP PROTECTION PRODUCTS SYNGENTA PARTICIPATIONS AG (CH) 2001-07-11 EP claimed
US-6228885-B1 Fungicidal compositions based on (N-phenylacetyl-N-2,6-XYLYL)methyl alaninate ISAGRO S.P.A. (IT) 2001-05-08 US claimed
US-6156740-A Synergistic fungicidal composition comprising a compound analogous to strobilurin RHONE-POULENC AGROCHIMIE (FR) 2000-12-05 US claimed
EP-0773720-B1 FUNGICIDAL COMPOSITION INCLUDING A 2-IMIDAZOLINE-5-ONE AVENTIS CROPSCIENCE SA (FR) 2000-10-18 EP claimed
CN-1244770-A Fungicidal compositions based on (N-phenylacetyl-N-2,6-xylyl) alaninate ISAGRO SPA (IT) 2000-02-16 CN claimed
EP-0741970-A1 BACTERICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-13 EP claimed
US-5516804-A FUNGICIDES FOR PLANTS BASF AKTIENGESELLSCHAFT (DE) 1996-05-14 US claimed
US-5395854-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1995-03-07 US claimed
EP-0547825-A2 Process for producing alpha-ketoamide derivative SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-06-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010046978-A1 Synergistic fungicidal composition comprising a compound analogous to strobilurin CHN2, CYTH2, CNPY3 HIF1A 2945/4885SMN1; SMN2 1546/4885MEN1 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.