Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.65 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.65 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144456 | 0.98 | TAS1R3 (0.65) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL5438188 | 0.92 | TAS1R3 (0.65) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL5429395 | 0.91 | TAS1R3 (0.66) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL13872407 | 0.90 | TAS1R3 (0.65) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| Hydrochloric Acid SCHEMBL4135083 | 0.89 | TAS1R3 (0.64) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL5429415 | 0.87 | TRPV4 (0.66) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL3920615 | 0.87 | TAS1R3 (0.59) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL14360828 | 0.86 | TAS1R3 (0.61) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL14360887 | 0.86 | TRPV4 (0.67) | TAS1R3TAS1R1TRPV4CTSBCTSS | |
| SCHEMBL5438961 | 0.85 | TAS1R3 (0.65) | TAS1R3TAS1R1TRPV4CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259965-A1 | Acyclic 1,3-Diamine And Uses Therefor | SMITHKLINE BEECHAM CORPORATION | 2007-11-08 | — | — | US | claimed |
| US-20070259965-A1 | Acyclic 1,3-Diamine And Uses Therefor | SMITHKLINE BEECHAM CORPORATION | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259965-A1 | Acyclic 1,3-Diamine And Uses Therefor | TRPV4, TRPC4, TRPV1 | TAS1R3 710/4885TAS1R1 618/4885TRPV4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.