SCHEMBL5434290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5429959	0.93	ADRB3 (0.41)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL5432002	0.90	ADRB2 (0.47)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL5433683	0.88	ADRB2 (0.45)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL5423178	0.88	ADRB2 (0.43)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL5434320	0.87	ADRB2 (0.43)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL5436285	0.87	ADRB2 (0.42)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL5943632	0.85	ADRB1 (0.35)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL23014462	0.84	ADRB2 (0.59)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL6428760	0.84	ADRB2 (0.59)	ADRB1ADRB2ADRB3DRD1SLC6A4
	SCHEMBL928498	0.84	ADRB2 (0.59)	ADRB1ADRB2ADRB3DRD1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.