Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21518266 | 0.83 | CA1 (0.36) | — | |
| SCHEMBL12858723 | 0.81 | MAPK1 (0.60) | MAPK1 | |
| SCHEMBL10468057 | 0.76 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL10467843 | 0.76 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL1683955 | 0.76 | — | — | |
| SCHEMBL16968086 | 0.74 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL19084378 | 0.74 | ADH1B (0.31) | — | |
| SCHEMBL3044357 | 0.72 | RIPK1 (0.31) | — | |
| SCHEMBL12038606 | 0.72 | MAPK1 (0.50) | MAPK1TDP1 | |
| SCHEMBL10383716 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354439-B2 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. | 2007-10-11 | — | — | US | disclosed |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | CHIHIRO MASATOSHI | 2007-05-10 | — | — | US | disclosed |
| EP-1130017-B1 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMA CO LTD (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-0957915-B1 | THIAZOLE DERIVATIVES FOR INHIBITION OF CYTOKINE PRODUCTION AND OF CELL ADHESION | OTSUKA PHARMA CO LTD (JP) | 2005-02-02 | — | — | EP | disclosed |
| US-20040014792-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO. LTD. | 2004-01-22 | — | — | US | disclosed |
| US-6583163-B2 | Using thiazole derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| EP-0934937-B1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMA CO LTD (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-RE37556-E1 | (ALKOXYPHENYL)THIAZOLE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-20020013469-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. | 2002-01-31 | — | — | US | disclosed |
| US-6291487-B1 | THIAZOLES SUBSTITUTED WITH A PHENYL AND A PYRIDYL GROUP | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1130017-A2 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6080764-A | PROTECTING VARIOUS TISSUE CELLS FROM DISTURBANCES ASSOCIATED WITH ISCHEMIA AND BLOOD REPERFUSION IN HEART, BRAIN, KIDNEY, LUNG AND DIGESTIVE TRACT BY INHIBITING SUPEROXIDE-RELEASE BY NEUTROPHILIC LEUKOCYTES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0957915-A1 | AGENT FOR INHIBITION OF CYTOKINE PRODUCTION AND AGENT FOR INHIBITION OF CELL ADHESION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-24 | — | — | EP | disclosed |
| EP-0934937-A1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998014191-A1 | AGENT FOR INHIBITION OF CYTOKINE PRODUCTION AND AGENT FOR INHIBITION OF CELL ADHESION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-09 | — | — | WO | disclosed |
| US-5677319-A | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5643932-A | PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0513387-A1 | ACTIVE OXYGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | MAPK1 591/4885TDP1 4805/4885 |
| US-20040014792-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, SELL, IL1RN | MAPK1 549/4885TDP1 4800/4885 |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | MAPK1 589/4885TDP1 4806/4885 |
| US-20020013469-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, SELL, IL1RN | MAPK1 549/4885TDP1 4800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.