SCHEMBL543508

SCHEMBL543508

CCCc1cc2cc3c(cc2cc1CCC)C(O)c1cc2cc(CCC)c(CCC)cc2cc1C3O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.34
GPR84 Q9NQS5 1/20 0.32
PTPN1 P18031 1/20 0.32
PTPN11 Q06124 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543208 0.91 GPR84 (0.40) GPR84
SCHEMBL3466279 0.78 HMGCR (0.38) HMGCRGPR84PTPN1PTPN11
SCHEMBL543810 0.77 TLR8 (0.47)
SCHEMBL543701 0.74 ALDH1A1 (0.40) GPR84
SCHEMBL5751431 0.73 HMGCR (0.41) HMGCRGPR84PTPN1PTPN11
SCHEMBL9487271 0.69 HMGCR (0.42) HMGCRPTPN1PTPN11
SCHEMBL27587538 0.68 GPR84 (0.44) GPR84
SCHEMBL5159924 0.67 GPR84 (0.46) GPR84
SCHEMBL542989 0.67 ELANE (0.37) HMGCRGPR84PTPN1PTPN11
SCHEMBL543504 0.67 GPR84 (0.33) HMGCRGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1719749-B1 POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM ASAHI CHEMICAL IND (JP) 2016-08-24 EP disclosed
US-8236998-B2 Polyacene compound and organic semiconductor thin film ASAHI KASEI CORPORATION (JP) 2012-08-07 US disclosed
US-20120108850-A1 POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM NAGATA KAZUTO (JP) 2012-05-03 US disclosed
US-8110714-B2 High mobility, solubility, oxidation resistance; transistor; drain electrodes ASAHI KASEI CORPORATION (JP) 2012-02-07 US disclosed
US-20080061287-A1 Polyacene Compound And Organic Semiconductor Thin Film ASAHI KASEI CORPORATION (JP) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108850-A1 POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM ZRANB2, PUF60, ZKSCAN2 HMGCR 2031/4885GPR84 3305/4885PTPN1 2337/4885
US-20080061287-A1 Polyacene Compound And Organic Semiconductor Thin Film ZRANB2, PUF60, ZKSCAN2 HMGCR 2031/4885GPR84 3305/4885PTPN1 2337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.