SCHEMBL543547

SCHEMBL543547

CC(C)Oc1ccccc1N[C]=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
ACHE P22303 1/20 0.45
IRAK4 Q9NWZ3 2/20 0.43
MRGPRX1 Q96LB2 1/20 0.40
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 2/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
PTGES2 Q9H7Z7 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2096191 0.83 KMT2A (0.39) LMNAMEN1RAB9AKMT2AL3MBTL1
SCHEMBL7534795 0.81 KMT2A (0.51) ALDH1A1MAPTMEN1NPC1RAB9A
SCHEMBL227124 0.79 ALDH1A1 (0.48) ALDH1A1LMNAMAPTNPC1MAPK1
SCHEMBL11472066 0.78 TSHR (0.41) LMNATDP1MAPK1KMT2AL3MBTL1
SCHEMBL2095787 0.76 ALDH1A1 (0.50) ALDH1A1ACHEIRAK4MRGPRX1LMNA
SCHEMBL16625020 0.75 ALDH1A1 (0.44) ALDH1A1ACHEIRAK4MRGPRX1LMNA
SCHEMBL2095784 0.75 ALDH1A1 (0.44) ALDH1A1ACHEIRAK4MRGPRX1LMNA
SCHEMBL31130258 0.75 IRAK4 (0.47) ALDH1A1ACHEIRAK4MRGPRX1LMNA
SCHEMBL31540608 0.75 ALDH1A1 (0.44) ALDH1A1ACHEIRAK4MRGPRX1LMNA
SCHEMBL2095895 0.74 GAA (0.36) LMNAMAPTNPC1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220413384-A1 PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-12-29 US disclosed
EP-2354187-B1 DISPERSED COMPOSITION, POLYMERIZABLE COMPOSITION, LIGHT SHIELDING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, LIQUID CRYSTAL DISPLAY DEVICE, WAFER-LEVEL LENS, AND IMAGING UNIT FUJIFILM CORP (JP) 2016-03-02 EP disclosed
US-9110205-B2 Black curable composition, light-shielding color filter, light-shielding film and method for manufacturing the same, wafer level lens, and solid-state imaging device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
EP-2037323-B1 Photosensitive compositions FUJIFILM CORP (JP) 2014-12-10 EP disclosed
US-8895909-B2 Photosensitive resin composition, light-shielding color filter, method of producing the same and solid-state image sensor FUJIFILM CORPORATION (JP) 2014-11-25 US disclosed
US-8872099-B2 Solid-state image sensor including a light-shielding color filter formed from a photosensitive resin composition, photosensitive resin composition and method of producing a light-shielding color filter FUJIFILM CORPORATION (JP) 2014-10-28 US disclosed
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-20130306919-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER, METHOD OF PRODUCING THE SAME AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2013-11-21 US disclosed
US-8470502-B2 Photosensitive resin composition, color filter and method of producing the same, and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-06-25 US disclosed
US-20020065194-A1 Guanidine compound and heat sensitive recording material FUJI PHOTO FILM CO., LTD. 2002-05-30 US disclosed
US-6348529-B1 THERMOSENSITIVE RECORDING WITH TWO ETHERS AND TWO GUANIDINE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 2002-02-19 US disclosed
US-6346359-B1 FORMS COLOR BY REACTION WITH DIAZONIUM SALT; COLORFASTNESS, STORAGE STABILITY, SHELF LIFE; PURPLE AND CYAN HUES FUJI PHOTO FILM CO., LTD. (JP) 2002-02-12 US disclosed
US-20020010330-A1 Method of preparing pyrrolotriazin-4-one compound and method of preparing isothiocyanatoformic acid ester derivative that is a reactant used for preparing pyrrolotriazin-4-one compound FUJI PHOTO FILM CO., LTD. 2002-01-24 US disclosed
US-6329116-B1 CYAN COUPLER AND A DIAZONIUM SALT COMPOUND, EXCELLENT SHELF LIFE, IMAGE LIGHT-RESISTANCE, IMAGE FIXING, EXCELLENT HUE AND COLOR DENSITY, PREFERABLY MICROENCAPSULATED IN POLYURETHANE OR POLYUREA FUJI PHOTO FILM CO., LTD. (JP) 2001-12-11 US disclosed
US-6316605-B1 FOR USE IN RECORDING MATERIALS FOR THERMAL TRANSFER RECORDING, INK JET RECORDING FUJI PHOTO FILM CO., LTD. (JP) 2001-11-13 US disclosed
US-6228553-B1 SHELF LIFE, STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2001-05-08 US disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed
US-5864043-A CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST KARL THOMAE GMBH (DE) 1999-01-26 US disclosed
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010330-A1 Method of preparing pyrrolotriazin-4-one compound and method of preparing isothiocyanatoformic acid ester derivative that is a reactant used for preparing pyrrolotriazin-4-one compound PPOX, QPCT, DDT ALDH1A1 461/4885ACHE 1680/4885IRAK4 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.