Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 3/20 | 0.44 |
| ▸ | TGM1 | P22735 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14490321 | 0.90 | GPR119 (0.44) | GPR119SYKNAMPTF13A1TGM2 | |
| SCHEMBL14490327 | 0.88 | SYK (0.44) | GPR119SYKNAMPTF13A1TGM2 | |
| SCHEMBL5440869 | 0.86 | NAMPT (0.57) | GPR119SYKNAMPTF13A1TGM2 | |
| SCHEMBL3038682 | 0.85 | SYK (0.50) | GPR119SYKNAMPTF13A1TGM2 | |
| SCHEMBL5445747 | 0.84 | GPR119 (0.51) | GPR119SYKNAMPTF13A1TGM2 | |
| SCHEMBL5444087 | 0.83 | NAMPT (0.54) | GPR119SYKNAMPTF13A1TGM2 | |
| SCHEMBL14490207 | 0.82 | TGM2 (0.64) | GPR119SYKF13A1TGM2TGM1 | |
| SCHEMBL3591634 | 0.81 | GPR119 (0.46) | GPR119NAMPTL3MBTL1MAPTCCNK | |
| SCHEMBL14490299 | 0.80 | GPR119 (0.50) | GPR119SYKMAPTCCNKCCNA2 | |
| SCHEMBL5447139 | 0.79 | TGM2 (0.60) | F13A1TGM2TGM1CCNKCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | ABL1, KDR, BCR | GPR119 2201/4885SYK 597/4885NAMPT 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.