Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59241 | 0.84 | APP (0.58) | APPMAPTTDP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL2859882 | 0.83 | APP (0.57) | APPMAPTTDP1ALDH1A1MAPK1 | |
| SCHEMBL30167806 | 0.78 | TP53 (0.59) | MAPK1HTTTP53CYP3A4KDM4E | |
| SCHEMBL315808 | 0.78 | TP53 (0.59) | MAPK1HTTTP53CYP3A4KDM4E | |
| 1,3-Diethoxybenzene SCHEMBL6565543 | 0.76 | TP53 (0.57) | ALDH1A1MAPK1HTTTP53CYP3A4 | |
| SCHEMBL29636353 | 0.76 | HTR3E (0.57) | MAPTTDP1ALDH1A1TP53KMT2A | |
| SCHEMBL60096 | 0.76 | HTR3E (0.57) | MAPTTDP1ALDH1A1TP53KMT2A | |
| Hydrochloric Acid SCHEMBL2868926 | 0.74 | HTR3E (0.55) | MAPTTDP1ALDH1A1TP53KMT2A | |
| SCHEMBL7455570 | 0.72 | APP (0.60) | APPALDH1A1MAPK1NOS1NOS2 | |
| SCHEMBL11524158 | 0.72 | TP53 (0.57) | APPMAPTTDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070141485-A1 | MULTILAYERED IMAGING ELEMENT | CITICORP NORTH AMERICA, INC., AS AGENT | 2007-06-21 | — | — | US | disclosed |