Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2859882 | 0.98 | APP (0.57) | APPTP53CYP3A4NOS1NOS2 | |
| SCHEMBL7455570 | 0.86 | APP (0.60) | APPNOS1NOS2ALDH1A1TSHR | |
| SCHEMBL11524158 | 0.86 | TP53 (0.57) | APPTP53CYP3A4ALDH1A1TSHR | |
| SCHEMBL9911816 | 0.85 | APP (0.55) | APPNOS1NOS2TSHR | |
| SCHEMBL5436864 | 0.84 | APP (0.46) | APPTP53CYP3A4NOS1NOS2 | |
| SCHEMBL12251463 | 0.83 | TP53 (0.50) | APPTP53CYP3A4ALDH1A1TSHR | |
| SCHEMBL7022072 | 0.83 | FAAH (0.56) | APPTSHRLTA4HCYP1A2CYP2D6 | |
| SCHEMBL1760671 | 0.82 | ALDH1A1 (0.55) | APPTP53CYP3A4ALDH1A1NQO1 | |
| SCHEMBL31339101 | 0.82 | ALDH1A1 (0.55) | APPTP53CYP3A4ALDH1A1NQO1 | |
| SCHEMBL24300289 | 0.82 | TP53 (0.49) | APPTP53CYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514521-A | IRON ARENE INITIATOR, ANILINE SENSITIZER, CYANINE SENSITIZER, ACRYLATE MONOMER | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 1996-05-07 | — | — | US | claimed |
| US-4508897-A | CONDENSATION OF AN ANILINE AND THE PRODUCT OF A QUINOLINIC ANHYDRI | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | claimed |
| US-20220112206-A1 | HETEROCYCLIC LSF INHIBITORS AND THEIR USES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-04-14 | — | — | US | disclosed |
| US-11242353-B2 | Heterocyclic LSF inhibitors and their uses | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-02-08 | — | — | US | disclosed |
| US-11242353-B2 | Heterocyclic LSF inhibitors and their uses | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-02-08 | — | — | US | disclosed |
| US-20210230173-A1 | HETEROCYCLIC LSF INHIBITORS AND THEIR USES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-07-29 | — | — | US | disclosed |
| WO-2021150835-A1 | HETEROCYCLIC LSF INHIBITORS AND THEIR USES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021150835-A1 | HETEROCYCLIC LSF INHIBITORS AND THEIR USES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-07-29 | — | — | WO | disclosed |
| US-20210230173-A1 | HETEROCYCLIC LSF INHIBITORS AND THEIR USES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-07-29 | — | — | US | disclosed |
| EP-1964860-B1 | ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER | TOSOH CORP (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-9101635-B2 | Inhibitors of filovirus entry into host cells | MICROBIOTIX, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-4788124-A | IONIC DYE-REACTIVE COUNTER ION COMPOUND | THE MEAD CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4772530-A | XANTHENE AND OXONOL DYES | THE MEAD CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4772541-A | SENSITIVE AT LONGER WAVELENGTHS | THE MEAD CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0277034-A2 | Lamination of two substrates | THE MEAD CORPORATION (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4751102-A | FOR PHOTOHARDENABLE FREE RADICAL ADDITION POLYMERIZABLE OR CROSSLINKABLE COMPOUND | THE MEAD CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0223587-A1 | Photosensitive materials containing ionic dye compounds as initiators | THE MEAD CORPORATION (US) | 1987-05-27 | — | — | EP | disclosed |
| US-4251446-A | COLOR PRECURSORS | STERLING DRUG INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4119622-A | Pyrazolonylazoaniline or aminonaphtyl compounds for copying processes | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-10 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242353-B2 | Heterocyclic LSF inhibitors and their uses | PCLAF, FLI1, GTF2F1 | APP 4174/4885TP53 16/4885CYP3A4 3484/4885 |
| US-20210230173-A1 | HETEROCYCLIC LSF INHIBITORS AND THEIR USES | PCLAF, FLI1, GTF2F1 | APP 4174/4885TP53 16/4885CYP3A4 3484/4885 |
| US-20220112206-A1 | HETEROCYCLIC LSF INHIBITORS AND THEIR USES | PCLAF, FLI1, GTF2F1 | APP 4174/4885TP53 16/4885CYP3A4 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.