Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446381 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL26655462 | 0.91 | MEN1 (0.48) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL23962222 | 0.89 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL6939385 | 0.89 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL6938048 | 0.89 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL5809555 | 0.89 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL6941001 | 0.89 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL6937043 | 0.89 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL21877272 | 0.89 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL11312574 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003485-A1 | Contrast agents | KLAVENESS JO | 2007-01-04 | — | — | US | disclosed |
| US-20050232865-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2005-10-20 | — | — | US | disclosed |
| US-20040131549-A1 | Ultrasonic diagnosis; crosslinked protein forming gas containing vesicles; stability; high speed elimination | NYCOMED IMAGING AS. | 2004-07-08 | — | — | US | disclosed |
| EP-0576521-B2 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2004-02-04 | — | — | EP | disclosed |
| US-20030031629-A1 | Contrast agents | NYCOMED IMAGING AS | 2003-02-13 | — | — | US | disclosed |
| US-5919753-A | Cross-linking agent | NYCOMED IMAGING AS (NO) | 1999-07-06 | — | — | US | disclosed |
| US-5693321-A | Polymers containing diester units | NYCOMED IMAGING AS (NO) | 1997-12-02 | — | — | US | disclosed |
| EP-0807441-A2 | Improvements in or relating to contrast agents | NYCOMED IMAGING AS (NO) | 1997-11-19 | — | — | EP | disclosed |
| EP-0576521-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1997-09-03 | — | — | EP | disclosed |
| US-5534250-A | METHYLENE DIESTER GROUPS, BIODEGRADABLE | NYCOMED IMAGING AS (NO) | 1996-07-09 | — | — | US | disclosed |
| US-5529766-A | Contrast agents | NYCOMED IMAGING AS (NO) | 1996-06-25 | — | — | US | disclosed |
| EP-0547126-B1 | BIODEGRADABLE POLYMERS CONTAINING DIESTER UNITS | NYCOMED IMAGING AS (NO) | 1996-02-28 | — | — | EP | disclosed |
| EP-0577659-B1 | CROSS-LINKING AGENT | NYCOMED IMAGING AS (NO) | 1996-01-17 | — | — | EP | disclosed |
| EP-0577659-A1 | CROSS-LINKING AGENT. | HOLMES MICHAEL JOHN (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0547126-A1 | POLYMERS CONTAINING DIESTER UNITS. | NYCOMED IMAGING AS (NO) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992017436-A1 | CROSS-LINKING AGENT | HOLMES, MICHAEL, JOHN (GB) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992004392-A1 | POLYMERS CONTAINING DIESTER UNITS | HOLMES, MICHAEL, JOHN (GB) | 1992-03-19 | — | — | WO | disclosed |