SCHEMBL5446381

SCHEMBL5446381

O=C(OCCl)OCCOC(=O)OCCl

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5438166 0.92 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL575095 0.90
SCHEMBL575094 0.88
SCHEMBL21012567 0.87 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL6932478 0.87 TSHR (0.41) ALDH1A1TSHR
SCHEMBL8452051 0.86 TSHR (0.41) ALDH1A1TSHR
SCHEMBL11322068 0.86
SCHEMBL21611812 0.84
SCHEMBL2222721 0.84
SCHEMBL16904015 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070003485-A1 Contrast agents KLAVENESS JO 2007-01-04 US disclosed
US-20050232865-A1 Contrast agents GE HEALTHCARE AS (NO) 2005-10-20 US disclosed
US-20040131549-A1 Ultrasonic diagnosis; crosslinked protein forming gas containing vesicles; stability; high speed elimination NYCOMED IMAGING AS. 2004-07-08 US disclosed
EP-0576521-B2 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-02-04 EP disclosed
US-20030031629-A1 Contrast agents NYCOMED IMAGING AS 2003-02-13 US disclosed
EP-0627942-B1 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1999-09-15 EP disclosed
US-5919753-A Cross-linking agent NYCOMED IMAGING AS (NO) 1999-07-06 US disclosed
US-5795562-A BIODEGRADABLE POLYMER AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING NYCOMED IMAGING AS (NO) 1998-08-18 US disclosed
US-5693321-A Polymers containing diester units NYCOMED IMAGING AS (NO) 1997-12-02 US disclosed
EP-0807441-A2 Improvements in or relating to contrast agents NYCOMED IMAGING AS (NO) 1997-11-19 EP disclosed
US-5534250-A METHYLENE DIESTER GROUPS, BIODEGRADABLE NYCOMED IMAGING AS (NO) 1996-07-09 US disclosed
US-5529766-A Contrast agents NYCOMED IMAGING AS (NO) 1996-06-25 US disclosed
EP-0547126-B1 BIODEGRADABLE POLYMERS CONTAINING DIESTER UNITS NYCOMED IMAGING AS (NO) 1996-02-28 EP disclosed
EP-0577659-B1 CROSS-LINKING AGENT NYCOMED IMAGING AS (NO) 1996-01-17 EP disclosed
EP-0627942-A1 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1994-12-14 EP disclosed
EP-0576521-A1 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS. NYCOMED IMAGING AS (NO) 1994-01-05 EP disclosed
WO-1993017718-A1 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS NYCOMED IMAGING A/S (NO) 1993-09-16 WO disclosed
EP-0547126-A1 POLYMERS CONTAINING DIESTER UNITS. NYCOMED IMAGING AS (NO) 1993-06-23 EP disclosed
WO-1992017213-A1 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1992-10-15 WO disclosed
WO-1992004392-A1 POLYMERS CONTAINING DIESTER UNITS HOLMES, MICHAEL, JOHN (GB) 1992-03-19 WO disclosed