Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438174 | 1.00 | CYP2E1 (0.33) | CYP2E1KDM4EPOLBPRKAB2PRKAG1 | |
| SCHEMBL5434926 | 0.91 | ALDH1A1 (0.35) | KDM4EPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL14505508 | 0.91 | ALDH1A1 (0.35) | KDM4EPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL5434922 | 0.91 | ALDH1A1 (0.35) | KDM4EPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL5434702 | 0.91 | HDAC1 (0.34) | CYP2E1KDM4ECHEK1HDAC3HDAC1 | |
| SCHEMBL5434704 | 0.91 | HDAC1 (0.34) | CYP2E1KDM4ECHEK1HDAC3HDAC1 | |
| SCHEMBL5441475 | 0.88 | CHEK1 (0.41) | CYP2E1KDM4EPOLBCHEK1 | |
| SCHEMBL5441480 | 0.88 | CHEK1 (0.41) | CYP2E1KDM4EPOLBCHEK1 | |
| SCHEMBL5434596 | 0.86 | JAK2 (0.34) | CYP2E1KDM4ECHEK1HDAC1HDAC2 | |
| SCHEMBL5434601 | 0.86 | JAK2 (0.34) | CYP2E1KDM4ECHEK1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | TPMT, HAVCR2, MTAP | CYP2E1 105/4885KDM4E 2012/4885POLB 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.