Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985965 | 0.92 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8452792 | 0.91 | TSHR (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5435399 | 0.91 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL19999147 | 0.89 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10029735 | 0.86 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9435701 | 0.86 | TSHR (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL7267519 | 0.85 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8510669 | 0.85 | THRB (0.70) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8501236 | 0.85 | THRB (0.70) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8448405 | 0.85 | TSHR (0.62) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003485-A1 | Contrast agents | KLAVENESS JO | 2007-01-04 | — | — | US | disclosed |
| US-20050232865-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2005-10-20 | — | — | US | disclosed |
| US-20040131549-A1 | Ultrasonic diagnosis; crosslinked protein forming gas containing vesicles; stability; high speed elimination | NYCOMED IMAGING AS. | 2004-07-08 | — | — | US | disclosed |
| EP-0576521-B2 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2004-02-04 | — | — | EP | disclosed |
| US-20030031629-A1 | Contrast agents | NYCOMED IMAGING AS | 2003-02-13 | — | — | US | disclosed |
| US-5919753-A | Cross-linking agent | NYCOMED IMAGING AS (NO) | 1999-07-06 | — | — | US | disclosed |
| US-5693321-A | Polymers containing diester units | NYCOMED IMAGING AS (NO) | 1997-12-02 | — | — | US | disclosed |
| EP-0807441-A2 | Improvements in or relating to contrast agents | NYCOMED IMAGING AS (NO) | 1997-11-19 | — | — | EP | disclosed |
| EP-0576521-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1997-09-03 | — | — | EP | disclosed |
| US-5534250-A | METHYLENE DIESTER GROUPS, BIODEGRADABLE | NYCOMED IMAGING AS (NO) | 1996-07-09 | — | — | US | disclosed |
| US-5529766-A | Contrast agents | NYCOMED IMAGING AS (NO) | 1996-06-25 | — | — | US | disclosed |
| EP-0547126-B1 | BIODEGRADABLE POLYMERS CONTAINING DIESTER UNITS | NYCOMED IMAGING AS (NO) | 1996-02-28 | — | — | EP | disclosed |
| EP-0577659-B1 | CROSS-LINKING AGENT | NYCOMED IMAGING AS (NO) | 1996-01-17 | — | — | EP | disclosed |
| EP-0577659-A1 | CROSS-LINKING AGENT. | HOLMES MICHAEL JOHN (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0547126-A1 | POLYMERS CONTAINING DIESTER UNITS. | NYCOMED IMAGING AS (NO) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992017436-A1 | CROSS-LINKING AGENT | HOLMES, MICHAEL, JOHN (GB) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992004392-A1 | POLYMERS CONTAINING DIESTER UNITS | HOLMES, MICHAEL, JOHN (GB) | 1992-03-19 | — | — | WO | disclosed |