Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452089 | 0.93 | TSHR (0.74) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL8400045 | 0.91 | TSHR (0.75) | TSHRALDH1A1THRBHPGDATM | |
| SCHEMBL8598156 | 0.89 | TSHR (0.72) | TSHRALDH1A1THRBHPGDATM | |
| SCHEMBL5438432 | 0.85 | THRB (0.57) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL19066401 | 0.85 | TSHR (0.84) | TSHRALDH1A1THRBHPGDATM | |
| SCHEMBL14893 | 0.85 | TSHR (0.84) | TSHRALDH1A1THRBHPGDATM | |
| SCHEMBL11583525 | 0.85 | TSHR (0.84) | TSHRALDH1A1THRBHPGDATM | |
| SCHEMBL8452792 | 0.84 | TSHR (0.52) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL13465905 | 0.84 | ALDH1A1 (0.58) | TSHRALDH1A1HPGDATMTDP1 | |
| Decane SCHEMBL5401080 | 0.83 | TSHR (0.74) | TSHRALDH1A1THRBTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627942-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1999-09-15 | — | — | EP | disclosed |
| US-5795562-A | BIODEGRADABLE POLYMER AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | NYCOMED IMAGING AS (NO) | 1998-08-18 | — | — | US | disclosed |
| US-5676925-A | USING POLYESTER OR ACRYLATE POLYMERS | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5674468-A | A BIODEGRADABLE POLYESTER; USEFUL IN DIAGNOSTIC APPLICATIONS SUCH AS ULTRASOUND AND MAGNETIC RESONANCE IMAGING | NYCOMED IMAGING AS (NO) | 1997-10-07 | — | — | US | disclosed |
| US-5574097-A | NONCROSSLINKED POLYMERS WITH BIODEGRADABLE LIPOPHILIC SIDE CHAINS INCORPORATING METHYLENE DIESTER UNITS, CLEAVABLE TO YIELD A WATER SOLUBLE POLYMER | NYCOMED IMAGING AS (NO) | 1996-11-12 | — | — | US | disclosed |
| EP-0629214-B1 | CHEMICAL COMPOUNDS | NYCOMED IMAGING AS (NO) | 1996-10-23 | — | — | EP | disclosed |
| EP-0629214-A1 | CHEMICAL COMPOUNDS. | NYCOMED IMAGING AS (NO) | 1994-12-21 | — | — | EP | disclosed |
| EP-0627942-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017718-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 1993-09-16 | — | — | WO | disclosed |
| WO-1993018070-A1 | CHEMICAL COMPOUNDS | NYCOMED IMAGING AS (NO) | 1993-09-16 | — | — | WO | disclosed |