SCHEMBL543878

SCHEMBL543878

CCC(C)(C)c1ccccc1C(=O)OO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.43
ALDH1A1 P00352 4/20 0.41
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 2/20 0.38
ELANE P08246 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.36
NR1I2 O75469 1/20 0.36
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL166714 0.88 NPC1 (0.41) TSHRALDH1A1NPC1L3MBTL1NPSR1
SCHEMBL15018 0.87 ALDH1A1 (0.42) TSHRALDH1A1NPC1L3MBTL1NPSR1
SCHEMBL1788945 0.86 TSHR (0.50) TSHRALDH1A1L3MBTL1NPSR1HSD17B10
SCHEMBL29460295 0.85 TDP1 (0.60) TSHRALDH1A1NPC1L3MBTL1NPSR1
SCHEMBL3074634 0.85 NPC1 (0.39) TSHRALDH1A1NPC1L3MBTL1TDP1
SCHEMBL28330842 0.85 TAAR1 (0.40) TSHRALDH1A1NPC1L3MBTL1TDP1
SCHEMBL1791574 0.85 TSHR (0.65) TSHRALDH1A1L3MBTL1NPSR1TDP1
SCHEMBL29988494 0.84 TDP1 (0.48) TSHRALDH1A1NPC1L3MBTL1NPSR1
SCHEMBL1414293 0.84 TDP1 (0.48) TSHRALDH1A1NPC1L3MBTL1NPSR1
SCHEMBL27145517 0.83 TSHR (0.41) TSHRALDH1A1NPC1L3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3755675-B1 ACCELERATED PEROXIDE-CURED RESIN COMPOSITIONS HAVING EXTENDED OPEN TIMES ARKEMA INC (US) 2026-05-13 EP claimed
US-20250353967-A1 CURABLE SILOXANE RESIN COMPOSITION AND FILM INCLUDING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-20 US claimed
EP-3559335-B1 LIQUID COMPOSITION COMPRISING TWO INITIATORS, ITS PROCESS OF POLYMERIZATION, USE AND MATERIAL OR COMPOSITION OBTAINED FOLLOWING POLYMERIZATION OF COMPOSITION ARKEMA FRANCE (FR) 2025-11-12 EP claimed
EP-4630461-A1 USE OF AT LEAST ONE PERESTER TO INITIATE THE POLYMERISATION OR COPOLYMERISATION OF ETHYLENE UNDER HIGH PRESSURE ARKEMA France (FR) 2025-10-15 EP claimed
US-12331164-B2 Curable siloxane resin composition KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-06-17 US claimed
CN-119857451-A Methyl methacrylate polymer preparation device and preparation method thereof 岚迪智慧科技(南通)有限公司 2025-04-22 CN claimed
US-20250092251-A1 MULTIPHASED POLYHYDROXYALKANOATE-BASED COMPOSITIONS AND ARTICLES MADE THEREFROM NEWLIGHT TECHNOLOGIES, INC. 2025-03-20 US claimed
EP-4479475-A2 MULTIPHASED POLYHYDROXYALKANOATE-BASED COMPOSITIONS AND ARTICLES MADE THEREFROM Newlight Technologies, Inc. (US) 2024-12-25 EP claimed
EP-3940008-B1 THERMOPLASTIC RESIN COMPOSITION INCLUDING COPOLYMER LG CHEMICAL LTD (KR) 2024-09-11 EP claimed
EP-3592735-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF TETROFOSMIN OR ACID ADDITION SALT THEREOF JUBILANT GENERICS LTD FORMERLY A DIVISION OF JUBILANT LIFE SCIENCES LTD (IN) 2024-03-20 EP claimed
EP-0445837-B1 Crosslinkable polyester/isocyanate compositions suitable for the preparation of composite materials SIR IND SPA (IT) 1997-01-08 EP claimed
US-5587434-A DEPOLYMERIZATION BY ADDING A FREE RADICAL GENERATOR; PROCESS CONTROL UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-12-24 US claimed
WO-1996037521-A1 BIMODALIZATION OF POLYMER MOLECULAR WEIGHT DISTRIBUTION EXXON CHEMICAL PATENTS INC. (US) 1996-11-28 WO claimed
US-5578682-A MOLECULAR WEIGHT CONTROL EXXON CHEMICAL PATENTS INC. (US) 1996-11-26 US claimed
EP-0506105-B1 Vulcanizable rubber composition DAIKIN IND LTD (JP) 1996-01-03 EP claimed
EP-0423639-B1 Peroxide masterbatches using polycaprolactone as the carrier ATOCHEM NORTH AMERICA (US) 1995-09-20 EP claimed
US-5382626-A Formation of polyurethanes and crosslinking with vinyl groups and unsaturated polyesters MONTEDISON S.P.A. (IT) 1995-01-17 US claimed
EP-0384431-B1 Process for making a propylene polymer with free-end long chain branching and use thereof HIMONT INC (US) 1994-11-30 EP claimed
EP-0259537-B1 PROCESS FOR REDUCING RESIDUAL MONOMERS IN LOW VISCOSITY POLYMER-POLYOLS ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1992-03-25 EP claimed
EP-0445837-A2 Crosslinkable polyester/isocyanate compositions suitable for the preparation of composite materials Montedison S.p.A. (IT) 1991-09-11 EP claimed