Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166714 | 0.86 | NPC1 (0.41) | NPC1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL543878 | 0.85 | TSHR (0.43) | NPC1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL28330842 | 0.83 | TAAR1 (0.40) | NPC1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL15018 | 0.82 | ALDH1A1 (0.42) | NPC1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL3074637 | 0.81 | TSHR (0.46) | TSHRTDP1L3MBTL1CYP3A4TP53 | |
| SCHEMBL29448528 | 0.80 | MAPT (0.44) | NPC1TSHRTDP1ELANEALDH1A1 | |
| SCHEMBL14976 | 0.80 | MAPT (0.44) | NPC1TSHRTDP1ELANEALDH1A1 | |
| SCHEMBL28053059 | 0.79 | CA1 (0.37) | NPC1TSHRCYP3A4ELANEALDH1A1 | |
| SCHEMBL30949796 | 0.79 | MAPT (0.43) | NPC1TSHRTDP1ELANEALDH1A1 | |
| Hydrogen Peroxide SCHEMBL8974942 | 0.79 | TDP1 (0.46) | NPC1TSHRTDP1L3MBTL1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943306-B1 | LOW TEMPERATURE INITIATORS FOR IMPROVING THE RUBBER PHASE VOLUME OF HIPS FORMULATIONS | FINA TECHNOLOGY (US) | 2012-07-18 | — | — | EP | claimed |
| EP-1408056-B1 | Preparation of expandable styrene polymers | ARKEMA INC (US) | 2008-04-23 | — | — | EP | claimed |
| EP-0506105-B1 | Vulcanizable rubber composition | DAIKIN IND LTD (JP) | 1996-01-03 | — | — | EP | claimed |
| US-7790081-B2 | Method of manufacturing formed product coated in mold | DAI NIPPON TORYO CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20050012241-A1 | Method of manufacturing formed product coated in mold | DAI NIPPON TORYO CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-0180789-B1 | CROSS-LINKING OF STYRENE POLYMERS | Luperox GmbH (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0180789-A1 | Cross-linking of styrene polymers | Luperox GmbH (DE) | 1986-05-14 | — | — | EP | disclosed |