Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.33 |
| ▸ | CCKAR | P32238 | 2/20 | 0.32 |
| ▸ | CCKBR | P32239 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452208 | 0.85 | CDYL (0.38) | CDYLCDY1; CDY1BCCKARCCKBRXDH | |
| SCHEMBL5444052 | 0.84 | SCN9A (0.40) | CDYLCDY1; CDY1BTLR9TLR8TLR7 | |
| SCHEMBL5444268 | 0.83 | CDYL (0.40) | CDYLCDY1; CDY1BCCKARCCKBRXDH | |
| SCHEMBL5445814 | 0.83 | CDYL (0.40) | CDYLCDY1; CDY1BCCKARCCKBRAGTR1 | |
| SCHEMBL5433300 | 0.82 | CYP3A4 (0.38) | CDYLCDY1; CDY1BXDH | |
| SCHEMBL5434235 | 0.82 | NPC1 (0.38) | CDYLCDY1; CDY1BCCKARCCKBRAGTR1 | |
| Trifluoroacetic Acid SCHEMBL5446298 | 0.81 | DPP4 (0.38) | CDYLCDY1; CDY1BTLR9TLR8TLR7 | |
| Trifluoroacetic Acid SCHEMBL5441107 | 0.80 | DPP4 (0.41) | CDYLCDY1; CDY1BTLR9TLR8TLR7 | |
| SCHEMBL5442594 | 0.79 | ALDH1A1 (0.33) | TLR8TLR7CCKARCCKBRXDH | |
| SCHEMBL5434729 | 0.77 | AVPR1B (0.35) | CCKARCCKBRXDHAGTR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007516158-A | — | — | 2007-06-21 | — | — | JP | claimed |
| EP-1613634-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-01-11 | — | — | EP | claimed |
| WO-2004087714-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-10-14 | — | — | WO | claimed |
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |
| EP-1613634-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087714-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | IDO1, NAT1, AANAT | CDYL 1358/4885CDY1; CDY1B 1235/4885ALK 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.